Motor improvement and spasms recovery with high-frequency 10 kHz spinal cord stimulation in a patient with spastic tetraparesis: beyond pain relief.

Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 9301980 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0932 (Electronic) Linking ISSN: 09406719 NLM ISO Abbreviation: Eur Spine J Subsets: MEDLINE

Original Publication: Heidelberg, Federal Republic of Germany : Springer-Verlag, c1992-

Spinal Cord Stimulation*/methods ; Quadriplegia*; Humans ; Male ; Treatment Outcome ; Recovery of Function/physiology ; Middle Aged ; Neuralgia/therapy ; Neuralgia/etiology ; Cervical Vertebrae ; Pain Management/methods ; Spasm/therapy ; Spasm/etiology

Purpose: To describe the clinical outcomes beyond pain relief of high-frequency spinal cord stimulation at 10 kHz (10 kHz SCS) in a patient with cervical myelopathy and drug-resistant chronic neuropathic pain with spastic tetraparesis.
Methods: A patient with C3-C6 myelomalacia and spastic tetraparesis previously treated with decompressive laminectomy underwent implantation of 10 kHz SCS for pain management through a trial procedure followed by permanent implantation. Due to the presence of epidural fibrotic scar tissue in the area of the previous C3-C6 laminectomy, the leads could not be implanted at the cervical level; therefore, the leads were positioned at the thoracic level. Data were collected during routine follow-up visits up to 15 months after implantation.
Results: Since the trialing phase and during all follow-up visits, along with complete pain relief in the lower limbs, a recovery from spasms was observed with an improvement in motor function. The patient recovered from a sensation of stiffness and difficulty in movement, with a significant decrease in muscle tone, regaining confidence in walking, and no longer needing assistance even for long walking distances. Although all disabling and painful symptomatology in the upper limbs instead did not ameliorate, the Oswestry Disability Index (ODI) score decreased from 50% at baseline to 6%.
Conclusion: To our knowledge, recovery from spasms and motor improvement in a spastic tetraparesis patient has never been reported before with 10 kHz SCS and possibly this new stimulation paradigm may overcome some performance limitations of traditional low-frequency SCS (LF-SCS). Treatment eliminated spasms at the lower limbs but not at the upper ones, thus suggesting that the location of the epidural leads could affect outcomes.
Competing Interests: Declarations. Competing interests: The authors have no relevant financial or non-financial interests to disclose. Conflict of interest: None of the authors has any potential conflict of interest. Consent to participate: The procedures performed including 10 kHz SCS trial and implantation of the IPG was part of the usual treatment plan for patients with drug-resistant neuropathic pain and was not part of a prospective study requiring Institutional Review Board approval. Consent to publish: The participant has consented to the submission of the case report to the journal.
(© 2024. The Author(s).)

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Keywords: Cervical myelopathy; Drug-resistant pain; High-frequency 10 kHz spinal cord stimulation; Spastic tetraparesis; Spasticity

Date Created: 20240925 Date Completed: 20241125 Latest Revision: 20241125

20241126

10.1007/s00586-024-08505-1

39322776