Consensus guidelines for the management of posterior fossa tumour for low- and middle-income countries.

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  • Additional Information
    • Corporate Authors:
      Pakistan Brain Tumour Consortium
    • Source:
      Publisher: Pakistan Medical Association Country of Publication: Pakistan NLM ID: 7501162 Publication Model: Print Cited Medium: Internet ISSN: 0030-9982 (Print) Linking ISSN: 00309982 NLM ISO Abbreviation: J Pak Med Assoc Subsets: MEDLINE
    • Publication Information:
      Publication: Karachi : Pakistan Medical Association
      Original Publication: Karachi.
    • Subject Terms:
      Infratentorial Neoplasms*/therapy ; Infratentorial Neoplasms*/surgery ; Medulloblastoma*/therapy ; Developing Countries*; Humans ; Cerebellar Neoplasms/therapy ; Cerebellar Neoplasms/pathology ; Astrocytoma/therapy ; Ependymoma/therapy ; Ependymoma/diagnosis ; Ependymoma/pathology ; Hemangioblastoma/therapy ; Hemangioblastoma/diagnosis ; Glioma/therapy ; Glioma/pathology ; Neurosurgical Procedures/methods ; Consensus
    • Abstract:
      The posterior fossa is a limited compartment therefore lesions compressing its structures can result in devastating outcomes. It can cause significant neurological deficit due to mass effect on critical structures and hydrocephalus. Due to the nature of the infratentorial region, urgent surgical intervention is often the first-line option. Surgical neuro-oncologists guide patients and caregivers through the course of this disease and to inform them about the various options for management and long-term outcome optimisation. There is currently conflicting data; however, institutional experiences can guide us towards achieving improvements in surgical outcomes and quality of life. Advances in molecular classifications coupled with highdose radiation treatment improve our capacity for improving overall survival in these patients. Common childhood tumours are ependymomas, medulloblastomas, and juvenile pilocytic astrocytomas, while adults often present with metastases, and less commonly, cerebellar haemangioblastomas and gliomas. This paper outlines management strategies with consideration for multidisciplinary care and resourcelimited settings.
    • Contributed Indexing:
      Investigator: MA Khokhar; M Tariq; SK Bakhshi; A Zaki; AA Qureshi; MT Khan; MS Shamim; F Javeed; RA Raja Memon; AT Khan; F Filza; M Ahmad; MA Saleem; M Arshad; AN Abbasi; M Nadeem; N Ashraf; NR Awan; AH Asghar; R Jooma; M Akram; A Bashir; NU Achakzai; S Ayub; MA Khan Rehmani; K Saeed; NZ Akhunzada; AS M Hashim; MM Alam; S Shams; T Abbas; AA Shah; M Arshad; S Butt; Z Sultan; SA Hamid; N Akhtar; B Khan; AA Laghari; M Usman; K Mahmood; SA Khan; AA Zahid; MA Shah; I Yousaf; S Sharif; A Jamshed; T Mahmood; M Ali; SB Anis; QUA Tariq; Y Rauf; T Shahab; B Ahmad; M Hussain; SS Bukhari; MA Mansha; M Shakir; ME Bari; G Javed; A Hafiz; F Najmuddin
      Keywords: Cerebellar neoplasms, medulloblastoma, caregivers, hemangioblastoma, astrocytoma, ependymoma, hydrocephalus, neuro-oncology, neurosurgery, brain tumour, posterior fossa.
    • Publication Date:
      Date Created: 20240912 Date Completed: 20240912 Latest Revision: 20241003
    • Publication Date:
      20241004
    • Accession Number:
      10.47391/JPMA.S3.GNO-22
    • Accession Number:
      39262080