Malignant transformation of an intraparenchymal hemangioma in the cervical spinal cord of a German shepherd dog.

Publisher: Wiley Periodicals Country of Publication: United States NLM ID: 8708660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-1676 (Electronic) Linking ISSN: 08916640 NLM ISO Abbreviation: J Vet Intern Med Subsets: MEDLINE

Publication: <2010-> : Malden, MA : Wiley Periodicals
Original Publication: Philadelphia : J.B. Lippincott Co., [c1987-

Dog Diseases*/pathology ; Dog Diseases*/diagnostic imaging ; Spinal Cord Neoplasms*/veterinary ; Spinal Cord Neoplasms*/pathology ; Spinal Cord Neoplasms*/diagnostic imaging ; Hemangioma*/veterinary ; Hemangioma*/pathology ; Hemangioma*/diagnostic imaging ; Hemangiosarcoma*/veterinary ; Hemangiosarcoma*/pathology ; Hemangiosarcoma*/diagnostic imaging ; Magnetic Resonance Imaging*/veterinary; Dogs ; Animals ; Female ; Cell Transformation, Neoplastic/pathology ; Cervical Vertebrae/pathology ; Cervical Vertebrae/diagnostic imaging ; Cervical Cord/pathology ; Cervical Cord/diagnostic imaging

An 8-year-old female spayed German shepherd dog was presented for evaluation of a 1-week history of right thoracic limb monoparesis. Magnetic resonance imaging (MRI) identified an intraparenchymal, T2 hypointense and T1 isointense, strongly heterogeneously contrast-enhancing mass with moderate internal susceptibility artifact on T2* images at the level of the cranial extent of the C5 vertebral body. Euthanasia was elected after a rapid neurologic decline in the 24 hours after MRI. Necropsy and histopathology identified an intraparenchymal hemangiosarcoma arising from a hemangioma in the cervical spinal cord, with no evidence of neoplastic disease in any other examined organs. The spectrum of vasoproliferative disorders in the central nervous system in veterinary species has been codified recently, but hemangiosarcoma is considered metastatic to the central nervous system. Herein we describe the clinical, imaging, and histologic findings in a dog with a novel primary location of hemangiosarcoma in the cervical spinal cord.
(© 2024 The Author(s). Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.)

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Keywords: canine; hemangioma; hemangiosarcoma; intraparenchymal; primary spinal cord neoplasia

Date Created: 20240911 Date Completed: 20240925 Latest Revision: 20240927

20240927

PMC11423490

10.1111/jvim.17190

39258518