Application and evaluation of minimally invasive surgical treatment options for early endometrial cancer.

Publisher: IOS Press Country of Publication: Netherlands NLM ID: 9314590 Publication Model: Print Cited Medium: Internet ISSN: 1878-7401 (Electronic) Linking ISSN: 09287329 NLM ISO Abbreviation: Technol Health Care Subsets: MEDLINE

Publication: Amsterdam : IOS Press
Original Publication: Amsterdam ; New York : Elsevier, c1993-

Endometrial Neoplasms*/surgery ; Endometrial Neoplasms*/pathology ; Robotic Surgical Procedures*/methods ; Laparoscopy*/methods ; Quality of Life*; Humans ; Female ; Middle Aged ; Retrospective Studies ; Aged ; Minimally Invasive Surgical Procedures/methods ; Neoplasm Staging ; Adult ; Neoplasm Recurrence, Local/surgery

Background: Laparoscopic and robotic-assisted techniques have gained popularity, and endometrial cancer (EC) remains a significant health problem among women.
Objective: Minimally invasive surgical (MIS) therapy options for early endometrial cancer will be evaluated for their effectiveness and safety is the aim of this paper. We also investigate the differences in oncologic outcomes between MIS and open surgery (OS) for individuals with early-stage EC. The patient was diagnosed with early-stage EC and treated with laparoscopic surgery and was the focus of a retrospective analysis. 162 patients with early EC were analyzed, with diagnoses occurring between 2002 and 2022.
Methods: The patients were fragmented into two groups, one for OS and another for laparoscopic procedures. The total tumor excision and recurrence rates were identical across the two methods, indicating similar oncologic results. Rates of complications were likewise comparable across the two groups.
Results: The quality of life ratings of patients with robotic-assisted surgery was higher than those with laparoscopic surgery. Sixty-two (62.2%) of the 162 patients in this research had OS, whereas Fifty-six (57.8%) had MIS. The probability of recurrence of EC from stages III to IV was significanitly higher in women who had OS.
Conclusion: Minimally invasive procedures were shown to be effective in treating early-stage EC, and while these findings provide support for their usage, larger multicenter randomized controlled studies are required to verify these results and further examine possible long-term advantages. Patients with early-stage EC, regardless of histologic type, had superior survival rates with MIS compared to OS.

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Keywords: Early stage; adjuvant treatment; endometrial cancer (EC); minimally invasive surgery (MIS); open surgery (OS)Highlights•Certain patients with endometrial cancer at an early stage may be candidates for minimally invasive surgical. •There are several benefits to treating early endometrial cancer with minimally invasive surgical.•Selecting patients for minimally invasive treatments of early-stage endometrial cancer and performing thorough preoperative evaluations are essential for maximizing the probability of success.

Date Created: 20240830 Date Completed: 20241109 Latest Revision: 20241205

20241209

PMC11613008

10.3233/THC-240439

39213110