Definitive radiotherapy and trismus in HNC patients: A critical review.

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  • Additional Information
    • Source:
      Publisher: Elsevier Scientific Publishers Country of Publication: Netherlands NLM ID: 8916049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0461 (Electronic) Linking ISSN: 10408428 NLM ISO Abbreviation: Crit Rev Oncol Hematol Subsets: MEDLINE
    • Publication Information:
      Publication: <2005->: Amsterdam : Elsevier Scientific Publishers
      Original Publication: Boca Raton, Fla. : CRC Press, 1983-
    • Subject Terms:
      Trismus*/etiology ; Trismus*/epidemiology ; Head and Neck Neoplasms*/radiotherapy ; Head and Neck Neoplasms*/complications; Humans ; Radiation Injuries/etiology ; Radiation Injuries/epidemiology ; Radiation Injuries/diagnosis ; Radiotherapy/adverse effects ; Radiotherapy Dosage
    • Abstract:
      Introduction: Trismus is a potentially critical morbidity following curative-intended radiotherapy in head and neck cancer patients. However, in this setting, evidence regarding this side effect remains to be fully defined, particularly in terms of dosimetric parameters.
      Materials and Methods: Key references were derived from a PubMed query. Hand searching and clinicaltrials.gov were also used.
      Results: This paper contains a narrative report and a critical discussion of the evidence on radiation-induced trismus in the literature, particularly the dosimetric concerns.
      Conclusions: The treatment goal should be to maintain high cure rates and limit the onset of complications. Further evaluations of dosimetric measures and clinical outcomes are warranted to identify patients at higher risk to target treatment tailoring.
      Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
      (Copyright © 2024 Elsevier B.V. All rights reserved.)
    • Contributed Indexing:
      Keywords: HNC; Head&Neck Cancer; IMRT; Modern Radiotherapy; Quality of Life; Radiation Toxicity; Trismus
    • Publication Date:
      Date Created: 20240828 Date Completed: 20240913 Latest Revision: 20240913
    • Publication Date:
      20240914
    • Accession Number:
      10.1016/j.critrevonc.2024.104486
    • Accession Number:
      39197668