Mapping Ethical, Legal, and Social Implications (ELSI) of gamete donation.

Publisher: Springer Country of Publication: Netherlands NLM ID: 9206495 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7330 (Electronic) Linking ISSN: 10580468 NLM ISO Abbreviation: J Assist Reprod Genet Subsets: MEDLINE

Publication: <2004- >: Amsterdam : Springer
Original Publication: New York : Plenum Press, c1992-

Oocyte Donation*/ethics ; Oocyte Donation*/legislation & jurisprudence ; Oocyte Donation*/psychology ; Reproductive Techniques, Assisted*/ethics ; Reproductive Techniques, Assisted*/legislation & jurisprudence ; Spermatozoa*; Female ; Humans ; Male ; Tissue Donors/ethics ; Tissue Donors/legislation & jurisprudence ; Tissue Donors/psychology

Research Question: This scoping review investigates the Ethical, Legal, and Social Implications (ELSI) of gamete donation, a critical facet of Assisted Reproductive Technologies, by analyzing the evolving research scope, methodological approaches, and the geographical skew in the literature. Despite the increased global uptake of donor gametes, current scholarship predominantly emanates from Western contexts and focuses on majoritized groups. This bias constrains the universality of research findings and limits their applicability across varied legal, cultural, and social contexts, underscoring a need for broader inclusivity.
Design: We addressed 867 pivotal articles published between 1999 and 2019.
Results: Our analysis reveals a discernible escalation in research volume, with 62% based on empirical research. The intellectual landscape unfolds into four dominant clusters: Regulatory Frameworks, Incentives, and Access; Family Dynamics and Genetic Linkages; Identity and Privacy in Donor Conception; and Cultural and Societal Attitudes towards GD. Each cluster highlights nuanced dimensions of gamete donation, from regulatory intricacies and psychological welfare to identity ethics and cultural perceptions.
Conclusion: Our findings advocate for a shift towards more globally representative and methodologically inclusive research. By integrating diverse cultural narratives and expanding geographical breadth, future research can offer holistic understandings of gamete donation, fostering equitable and culturally resonant practices and policies worldwide.
Competing Interests: Declarations. Ethics approval: This research did not involve human participants or animals and did not require any informed consent of any type. Consent to participate: Not required. The authors give a full consent to publish the article in the journal of assisted reproduction and genetics. Competing interests: The authors declare no competing interests.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

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Keywords: Egg donation; Ethical, Legal and Social Implications (ELSI); Gamete donation; Gaps in research; Geographic distribution of research; Scoping review; Sperm donation

Date Created: 20240825 Date Completed: 20241205 Latest Revision: 20241213

20241214

PMC11621250

10.1007/s10815-024-03229-z

39183224