Enhancing Pulmonary Embolism Detection in COVID-19 Patients Through Advanced Deep Learning Techniques.

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  • Additional Information
    • Source:
      Publisher: IOS Press Country of Publication: Netherlands NLM ID: 9214582 Publication Model: Print Cited Medium: Internet ISSN: 1879-8365 (Electronic) Linking ISSN: 09269630 NLM ISO Abbreviation: Stud Health Technol Inform Subsets: MEDLINE
    • Publication Information:
      Original Publication: Amsterdam ; Washington, DC : IOS Press, 1991-
    • Subject Terms:
      Pulmonary Embolism*/diagnostic imaging ; COVID-19* ; Deep Learning* ; Computed Tomography Angiography*/methods; Humans ; SARS-CoV-2 ; Pandemics
    • Abstract:
      The intersection of COVID-19 and pulmonary embolism (PE) has posed unprecedented challenges in medical diagnostics. The critical nature of PE and its increased incidence during the pandemic underline the need for improved detection methods. This study evaluates the effectiveness of advanced deep learning techniques in enhancing PE detection in post-COVID-19 patients through Computed Tomography Pulmonary Angiography (CTPA) scans. Using a dataset of 746 anonymized CTPA images from 25 patients, we fine-tuned the state-of-the-art Ultralytics YOLOv8 object detection model, which was trained on 676 images with 1,517 annotated bounding boxes and validated on 70 images with 108 bounding boxes. After 200 epochs of training, which lasted approximately 1.021 hours, the YOLOv8 model demonstrated significant diagnostic proficiency, achieving a mean Average Precision (mAP) of 0.683 at an IoU threshold of 0.50 and a mAP of 0.246 at the IoU range of 0.50:0.95 in the validation dataset. Notably, the model reached a maximum precision of 0.85949 and a maximum recall of 0.81481, though these metrics were observed in separate epochs. These findings emphasize the model's potential for high diagnostic accuracy and offer a promising direction for deploying AI tools in clinical settings, significantly contributing to healthcare innovation and patient care post-pandemic.
    • Contributed Indexing:
      Keywords: COVID-19; Pulmonary Embolism; artificial intelligence (AI); computed tomography (CT); deep learning
    • Publication Date:
      Date Created: 20240823 Date Completed: 20240823 Latest Revision: 20240823
    • Publication Date:
      20240823
    • Accession Number:
      10.3233/SHTI240622
    • Accession Number:
      39176593