Designing and additive manufacturing of talus implant for post-traumatic talus avascular necrosis: a case study.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X (Electronic) Linking ISSN: 1749799X NLM ISO Abbreviation: J Orthop Surg Res Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BioMed Central, 2006-
    • Subject Terms:
      Talus*/surgery ; Talus*/injuries ; Talus*/diagnostic imaging ; Prosthesis Design* ; Osteonecrosis*/surgery ; Osteonecrosis*/etiology ; Osteonecrosis*/diagnostic imaging; Humans ; Male ; Adult ; Alloys ; Titanium ; Prostheses and Implants ; Young Adult ; Finite Element Analysis ; Tomography, X-Ray Computed
    • Abstract:
      New technologies in additive manufacturing and patient-specific CT-based custom implant designs make it possible for previously unimaginable salvage and limb-sparing operations a practical reality. This study presents the design and fabrication of a lattice-structured implant for talus replacement surgery. Our primary case involved a young adult patient who had sustained severe damage to the talus, resulting in avascular necrosis and subsequent bone collapse. This condition caused persistent and debilitating pain, leading the medical team to consider amputation of the left foot at the ankle level as a last resort. Instead, we proposed a Ti6Al4V-based patient-specific implant with lattice structure specifically designed for pan-talar fusion. Finite element simulation is conducted to estimate its performance. To ensure its mechanical integrity, uniaxial compression experiments were conducted. The implant was produced using selective laser melting technology, which allowed for precise and accurate construction of the unique lattice structure. The patient underwent regular monitoring for a period of 24 months. At 2-years follow-up the patient successfully returned to activities without complication. The patient's functional status was improved, limb shortening was minimized.
      (© 2024. The Author(s).)
    • References:
      J Orthop Translat. 2023 Sep 01;42:94-112. (PMID: 37675040)
      J Bone Joint Surg Am. 2014 Jul 16;96(14):1211-1218. (PMID: 25031376)
      J Arthroplasty. 2020 Nov;35(11):3289-3299. (PMID: 32631725)
      Foot Ankle Spec. 2019 Feb;12(1):39-48. (PMID: 29537314)
      Bioact Mater. 2021 Dec 25;15:82-102. (PMID: 35386347)
      Foot Ankle Int. 2022 Jun;43(6):750-761. (PMID: 35209733)
      Mater Sci Eng C Mater Biol Appl. 2014 Oct;43:182-8. (PMID: 25175203)
      Acta Biomater. 2017 Apr 15;53:572-584. (PMID: 28213101)
      J Craniomaxillofac Surg. 2013 Oct;41(7):603-9. (PMID: 23333490)
      Foot Ankle Orthop. 2023 Jan 27;8(1):24730114221151068. (PMID: 36741680)
      Biofabrication. 2020 Oct 28;13(1):. (PMID: 33045688)
      Adv Mater. 2018 Apr;30(17):e1705708. (PMID: 29543352)
      Science. 1965 Nov 12;150(3698):893-9. (PMID: 5319761)
      Foot Ankle Orthop. 2021 Oct 26;6(4):24730114211043516. (PMID: 35097475)
      Clin Orthop Relat Res. 1992 Jan;(274):124-34. (PMID: 1728998)
      J Foot Ankle Surg. 2021 Jan-Feb;60(1):182-186. (PMID: 33218865)
      Foot Ankle Int. 2020 Jan;41(1):79-83. (PMID: 31559851)
      JB JS Open Access. 2020 Oct 28;5(4):. (PMID: 33283130)
      J Foot Ankle Surg. 2016 Nov - Dec;55(6):1292-1296. (PMID: 26387058)
      J Dent Res. 2021 Sep;100(10):1178-1185. (PMID: 34235985)
      J Orthop Surg Res. 2020 Feb 7;15(1):40. (PMID: 32028970)
      Front Bioeng Biotechnol. 2023 Jan 27;11:1117954. (PMID: 36777251)
      Foot Ankle Int. 2018 Aug;39(8):916-921. (PMID: 29648876)
      Foot Ankle Surg. 2022 Dec;28(8):1194-1201. (PMID: 36028440)
      J Biomed Mater Res A. 2014 Dec;102(12):4234-43. (PMID: 24497384)
      Adv Mater. 2012 Apr 3;24(13):1628-74. (PMID: 22396318)
      Curr Pharm Des. 2013;19(19):3446-55. (PMID: 23432675)
      Materials (Basel). 2021 Jul 12;14(14):. (PMID: 34300810)
      Acta Biomater. 2018 Oct 15;80:1-30. (PMID: 30248515)
      Foot Ankle Int. 2020 Dec;41(12):1529-1536. (PMID: 32806936)
      J Bone Joint Surg Am. 2022 May 4;104(9):790-795. (PMID: 35188906)
    • Grant Information:
      22IRF-05 Higher Education and Science Committee, Ministry of Education, Science, Culture and Sport RA; 22AA-2F022 Higher Education and Science Committee, Ministry of Education, Science, Culture and Sport RA; 22IRF-05 Higher Education and Science Committee, Ministry of Education, Science, Culture and Sport RA
    • Contributed Indexing:
      Keywords: Additive manufacturing; Customized implant; Simulation; Talus implant
    • Accession Number:
      0 (Alloys)
      D1JT611TNE (Titanium)
      12743-70-3 (titanium alloy (TiAl6V4))
    • Publication Date:
      Date Created: 20240822 Date Completed: 20240823 Latest Revision: 20240825
    • Publication Date:
      20240826
    • Accession Number:
      PMC11340157
    • Accession Number:
      10.1186/s13018-024-04948-w
    • Accession Number:
      39175072