Acute renal failure, COVID-19 and deaths, worrying rates in intensive care units: a cross-sectional study.

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  • Additional Information
    • Source:
      Publisher: Associação Paulista de Medicina Country of Publication: Brazil NLM ID: 100897261 Publication Model: eCollection Cited Medium: Internet ISSN: 1806-9460 (Electronic) Linking ISSN: 15163180 NLM ISO Abbreviation: Sao Paulo Med J Subsets: MEDLINE
    • Publication Information:
      Original Publication: São Paulo, S.P., Brazil : Associação Paulista de Medicina, [1994-
    • Subject Terms:
      COVID-19*/mortality ; COVID-19*/epidemiology ; Acute Kidney Injury*/mortality ; Acute Kidney Injury*/epidemiology ; Intensive Care Units*/statistics & numerical data; Humans ; Cross-Sectional Studies ; Male ; Female ; Middle Aged ; Aged ; Brazil/epidemiology ; Prevalence ; Adult ; SARS-CoV-2 ; Hospital Mortality ; Risk Factors ; Aged, 80 and over ; Renal Insufficiency, Chronic/mortality ; Renal Insufficiency, Chronic/epidemiology
    • Abstract:
      Background: Acute kidney failure is a serious consequence of coronavirus disease 2019 (COVID-19).
      Objectives: To identify the prevalence of COVID-19, kidney failure, frequency of death, and associated factors in patients receiving intensive care.
      Design and Setting: Analytical cross-sectional study conducted in the intensive care unit (ICU) of a medium-sized philanthropic general hospital in center-west Minas Gerais.
      Methods: Adults and older individuals who underwent real-time polymerase chain reaction testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were evaluated by the nephrology team.
      Results: Among the 176 patients, the prevalence of COVID-19 and acute kidney injury (AKI) were 103 (58.5%) and 132 (75%), respectively, and 44 (25%) had chronic kidney disease (CKD) and 16 (15,5%) were positive for SARS-CoV-2. In the Charlson index classification, which estimates the risk of death, a statistically significant difference was identified in the percentages of groups with and without COVID-19 for indices 0, 1, and 2. There was a significant association between kidney disease and ICU mortality (P < 0.05). Patients with CKD had fewer fatal outcomes (13/97, 13.4%) than those with AKI (85/97, 87.6%).
      Conclusions: COVID-19 rates remained high long after diagnosis and prevention of SARS-CoV-2 infection. In addition, a higher death rate among patients who developed AKI, whose prevalence was also greater than that in the national literature, regardless of the presence of COVID-19, revealed a worrying scenario and corroborated the need for early and judicious approaches to preserve the lives of patients with AKI admitted to intensive care units.
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    • Publication Date:
      Date Created: 20240821 Date Completed: 20240821 Latest Revision: 20241217
    • Publication Date:
      20241217
    • Accession Number:
      PMC11329267
    • Accession Number:
      10.1590/1516-3180.2023.0150.R1.13052024
    • Accession Number:
      39166611