An Updated Review on the Spatial Distribution of Borrelia burgdorferi Sensu Lato Across Ticks, Animals and Humans in Northeastern China and Adjacent Regions.

Publisher: Blackwell Verlag Country of Publication: Germany NLM ID: 101300786 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1863-2378 (Electronic) Linking ISSN: 18631959 NLM ISO Abbreviation: Zoonoses Public Health Subsets: MEDLINE

Original Publication: Berlin, Germany : Blackwell Verlag

Borrelia burgdorferi Group*/isolation & purification ; Lyme Disease*/epidemiology ; Lyme Disease*/veterinary ; Lyme Disease*/microbiology ; Lyme Disease*/transmission ; Ticks*/microbiology; Animals ; Humans ; Animals, Wild/microbiology ; China/epidemiology ; Livestock/microbiology ; Zoonoses

Background: Lyme disease is a tick-borne zoonotic disease caused by Borrelia burgdorferi sensu lato and is prevalent in northeastern Asia, particularly in the forested area of Northeastern China. However, a lack of systematic data on the spatial distribution of B. burgdorferi in this region hinders the prediction of its transmission risk across the landscape.
Methods: To provide an updated overview and establish a comprehensive spatial distribution database, we conducted a systematic review of literature published between 2000 and 2022. We collected and compiled relevant data on B. burgdorferi in Northeastern China and its neighbouring regions, outlining its distribution in ticks, wild animals, livestock and humans. Spatial analysis was performed to identify spatial clusters of tick positivity and host infection rates.
Results: From a total of 1823 literature, we selected 110 references to compile 626 detection records of B. burgdorferi, including 288 in ticks, 109 in wildlife, 111 in livestock and domestic animals and 100 in humans. The average detection rate of B. burgdorferi in ticks was approximately 20%, with wildlife, livestock and domestic animal host positivity rates below 50% and human seroprevalence rates varying from 0.94% to 44.18%.
Conclusions: The study identified the presence of 17 tick species and ten genotypes of B. burgdorferi in the region, indicating a broad distribution. Notably, B. burgdorferi exhibited notable clustering, particularly in the central and eastern areas of Jilin Province, warranting further investigation.
(© 2024 Wiley‐VCH GmbH. Published by John Wiley & Sons Ltd.)

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42107458 National Natural Science Foundation of China

Keywords: Borrelia burgdorferi sensu lato; infection prevalence; northeastern China; spatial distribution

Date Created: 20240816 Date Completed: 20241005 Latest Revision: 20241024

20241025

10.1111/zph.13176

39148261