A visual representation of the hand in the resting somatomotor regions of the human brain.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Original Publication: London : Nature Publishing Group, copyright 2011-

Hand*/physiology ; Magnetic Resonance Imaging* ; Brain Mapping* ; Visual Perception*/physiology; Humans ; Male ; Female ; Adult ; Young Adult ; Brain/physiology ; Brain/diagnostic imaging ; Motor Cortex/physiology ; Motor Cortex/diagnostic imaging ; Rest/physiology ; Photic Stimulation ; Visual Cortex/physiology ; Visual Cortex/diagnostic imaging

Hand visibility affects motor control, perception, and attention, as visual information is integrated into an internal model of somatomotor control. Spontaneous brain activity, i.e., at rest, in the absence of an active task, is correlated among somatomotor regions that are jointly activated during motor tasks. Recent studies suggest that spontaneous activity patterns not only replay task activation patterns but also maintain a model of the body's and environment's statistical regularities (priors), which may be used to predict upcoming behavior. Here, we test whether spontaneous activity in the human somatomotor cortex as measured using fMRI is modulated by visual stimuli that display hands vs. non-hand stimuli and by the use/action they represent. A multivariate pattern analysis was performed to examine the similarity between spontaneous activity patterns and task-evoked patterns to the presentation of natural hands, robot hands, gloves, or control stimuli (food). In the left somatomotor cortex, we observed a stronger (multivoxel) spatial correlation between resting state activity and natural hand picture patterns compared to other stimuli. No task-rest similarity was found in the visual cortex. Spontaneous activity patterns in somatomotor brain regions code for the visual representation of human hands and their use.
(© 2024. The Author(s).)

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No 759651 H2020 European Research Council

Keywords: Somatomotor area; Spontaneous activity; Task-evoked activity; fMRI

Date Created: 20240807 Date Completed: 20240807 Latest Revision: 20240812

20240813

PMC11306329

10.1038/s41598-024-69248-z

39112629