Recent advances of bone tissue engineering: carbohydrate and ceramic materials, fundamental properties and advanced biofabrication strategies ‒ a comprehensive review.

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  • Additional Information
    • Source:
      Publisher: Institute of Physics Pub Country of Publication: England NLM ID: 101285195 Publication Model: Electronic Cited Medium: Internet ISSN: 1748-605X (Electronic) Linking ISSN: 17486041 NLM ISO Abbreviation: Biomed Mater Subsets: MEDLINE
    • Publication Information:
      Original Publication: Bristol, UK : Institute of Physics Pub.,
    • Subject Terms:
      Tissue Engineering*/methods ; Bone and Bones*/chemistry ; Bone and Bones*/metabolism ; Ceramics* ; Carbohydrates*/chemistry; Humans ; Animals ; Carbohydrate Metabolism ; Biocompatible Materials ; Chemical Phenomena
    • Abstract:
      Bone is a dynamic tissue that can always regenerate itself through remodeling to maintain biofunctionality. This tissue performs several vital physiological functions. However, bone scaffolds are required for critical-size damages and fractures, and these can be addressed by bone tissue engineering. Bone tissue engineering (BTE) has the potential to develop scaffolds for repairing critical-size damaged bone. BTE is a multidisciplinary engineered scaffold with the desired properties for repairing damaged bone tissue. Herein, we have provided an overview of the common carbohydrate polymers, fundamental structural, physicochemical, and biological properties, and fabrication techniques for bone tissue engineering. We also discussed advanced biofabrication strategies and provided the limitations and prospects by highlighting significant issues in bone tissue engineering. There are several review articles available on bone tissue engineering. However, we have provided a state-of-the-art review article that discussed recent progress and trends within the last 3-5 years by emphasizing challenges and future perspectives.
      (© 2024 IOP Publishing Ltd. All rights, including for text and data mining, AI training, and similar technologies, are reserved.)
    • Contributed Indexing:
      Keywords: biofabrication strategies; bone tissue; carbohydrate polymers; polysaccharide; tissue engineering
    • Accession Number:
      0 (Carbohydrates)
      0 (Biocompatible Materials)
    • Publication Date:
      Date Created: 20240806 Date Completed: 20240829 Latest Revision: 20240829
    • Publication Date:
      20240830
    • Accession Number:
      10.1088/1748-605X/ad6b8a
    • Accession Number:
      39105493