Usefulness of Eye Deformation in the Corvis ST Measurement to Predict Postoperative Hypotony Complications in Glaucoma.

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  • Additional Information
    • Source:
      Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1891 (Electronic) Linking ISSN: 00029394 NLM ISO Abbreviation: Am J Ophthalmol Subsets: MEDLINE
    • Publication Information:
      Publication: 1999- : New York, NY : Elsevier Science
      Original Publication: [Chicago, etc., Ophthalmic Pub. Co., etc.]
    • Subject Terms:
      Intraocular Pressure*/physiology ; Ocular Hypotension*/physiopathology ; Ocular Hypotension*/etiology ; Ocular Hypotension*/diagnosis ; Trabeculectomy* ; Postoperative Complications* ; Tonometry, Ocular*; Humans ; Male ; Female ; Aged ; Middle Aged ; Aged, 80 and over ; Adult ; Glaucoma, Open-Angle/surgery ; Glaucoma, Open-Angle/physiopathology ; Alkylating Agents/administration & dosage ; Mitomycin/administration & dosage ; Axial Length, Eye/pathology ; Glaucoma/physiopathology ; Glaucoma/surgery ; Biomechanical Phenomena
    • Abstract:
      Purpose: This study aimed to investigate the usefulness of measuring biomechanical parameters using the Corvis ST to predict the occurrence of hypotony maculopathy and choroidal detachment (CD) following trabeculectomy or bleb needling revision with mitomycin C.
      Design: Clinical cohort study.
      Methods: This study included 100 eyes of 100 patients who underwent trabeculectomy (88 eyes of 88 patients) or bleb needling (12 eyes of 12 patients) with mitomycin C. A significant predictor of hypotony complications was identified from (1) operation (trabeculectomy or bleb needling), (2) age, (3) sex, (4) disease type (primary open-angle glaucoma, exfoliation glaucoma or other), (5) lens status (phakia or pseudophakia), (6) preoperative Goldmann applanation tonometry (GAT) intraocular pressure (IOP), (7) preoperative central corneal thickness (CCT), (8) preoperative axial length (AL), (9) preoperative anterior chamber depth, (10) "Min IOP" (IOP value when hypotony complications occurred, otherwise the minimum IOP during 3 months from trabeculectomy or bleb needling), (11) preoperative corneal curvature, and (12-24) 12 Corvis ST parameters using multivariate logistic regression.
      Results: There were 13 and 21 eyes developed hypotony maculopathy and CD, respectively. Male gender, greater preoperative GAT IOP, and greater highest concavity deflection Amplitude were significant predictors of the occurrence of hypotony maculopathy (P < .05). On the other hand, shorter AL, thinner CCT, greater preoperative GAT IOP and pseudophakia were significant predictors of the occurrence of CD (P < .05).
      Conclusions: A careful attention should be paid to the occurrence of hypotony maculopathy with male gender and greater highest concavity deflection Amplitude despite higher preoperative GAT IOP. Different risk factors were identified; shorter AL, thinner CCT, greater preoperative GAT IOP, and pseudophakia.
      (Copyright © 2024 Elsevier Inc. All rights reserved.)
    • Accession Number:
      0 (Alkylating Agents)
      50SG953SK6 (Mitomycin)
    • Publication Date:
      Date Created: 20240801 Date Completed: 20241128 Latest Revision: 20241128
    • Publication Date:
      20241202
    • Accession Number:
      10.1016/j.ajo.2024.07.031
    • Accession Number:
      39089353