Biovalorisation of agro-industrial wastes into astaxanthin by Xanthophyllomyces dendrorhous.

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  • Additional Information
    • Source:
      Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0614 (Electronic) Linking ISSN: 01757598 NLM ISO Abbreviation: Appl Microbiol Biotechnol Subsets: MEDLINE
    • Publication Information:
      Original Publication: Berlin ; New York : Springer International, c1984-
    • Subject Terms:
      Xanthophylls*/metabolism ; Industrial Waste* ; Culture Media*/chemistry ; Molasses* ; Fermentation* ; Basidiomycota*/metabolism; Biomass ; Industrial Microbiology/methods ; Glycine max/metabolism
    • Abstract:
      Astaxanthin is a red xanthophyll with high economic and industrial value in the pharmaceutical, nutraceutical, cosmetic and food industries. In recent years, the biotechnological production of astaxanthin has attracted much attention as a sustainable alternative to the predominating petrochemical-dependent chemical synthesis. In this regard, Xanthophyllomyces dendrorhous is regarded as a promising microorganism for industrial production of astaxanthin. Unfortunately, biotechnological production of the carotenoid is currently expensive. The present study investigated soy molasses (SM) and residual brewers' yeast as cheap fermentation feedstocks for the cultivation of X. dendrorhous and astaxanthin production. Yeast extract was obtained from residual brewers' yeast using various techniques and then combined with SM to formulate a two-component growth medium which was subsequently used to cultivate X. dendrorhous. Generally, the yeast extract produced from residual brewers' yeast supported X. dendrorhous growth and astaxanthin production at levels comparable to those seen with commercial yeast extract. Overall, cultivating X. dendrorhous in an SM-based medium containing 5% SM and 0.2% yeast extract obtained from residual brewers' yeast resulted in significantly higher (> 20% more) biomass accumulation compared to the control media (YPD). A similar slightly higher astaxanthin output (up to 14% more) was recorded in the SM-based medium compared to YPD. The formulated cultivation medium in this study provides an opportunity to reduce the production cost of astaxanthin from X. dendrorhous while simultaneously reducing the environmental impact related to the disposal of the industrial waste used as feedstock. KEY POINTS: • Cheap culture media were formulated from soy molasses and brewers' spent yeast • The formulated medium resulted in at least 20% more biomass than the control • Up to 14% more astaxanthin was produced in molasses-based medium.
      (© 2024. The Author(s).)
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    • Grant Information:
      24-16-20054 Russian Science Foundation
    • Contributed Indexing:
      Keywords: P. rhodozyma; Agro-industrial by-products; Bioconversion; Ketocarotenoid; Soy molasses; Sustainability
    • Accession Number:
      8XPW32PR7I (astaxanthine)
      0 (Xanthophylls)
      0 (Industrial Waste)
      0 (Culture Media)
    • Publication Date:
      Date Created: 20240727 Date Completed: 20240728 Latest Revision: 20240730
    • Publication Date:
      20240730
    • Accession Number:
      PMC11283421
    • Accession Number:
      10.1007/s00253-024-13257-5
    • Accession Number:
      39066896