Stop H5N1 influenza in US cattle now.

Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Publication: : Washington, DC : American Association for the Advancement of Science
Original Publication: New York, N.Y. : [s.n.] 1880-

Cattle Diseases*/epidemiology ; Cattle Diseases*/prevention & control ; Cattle Diseases*/virology ; Disease Outbreaks*/prevention & control ; Disease Outbreaks*/veterinary ; Influenza A Virus, H5N1 Subtype*/pathogenicity ; Influenza in Birds*/epidemiology ; Influenza in Birds*/transmission ; Influenza in Birds*/virology ; Orthomyxoviridae Infections*/epidemiology ; Orthomyxoviridae Infections*/prevention & control ; Orthomyxoviridae Infections*/veterinary ; Orthomyxoviridae Infections*/virology; Animals ; Cattle ; Humans ; Birds/virology ; Poultry/virology ; United States/epidemiology

The relentless march of a highly pathogenic avian influenza virus (HPAIV) strain, known as H5N1, to become an unprecedented panzootic continues unchecked. The leap of H5N1 clade 2.3.4.4b from Eurasia and Africa to North America in 2021 and its further spread to South America and the Antarctic have exposed new avian and mammalian populations to the virus and led to outbreaks on an unrivaled scale. The virus has infected wild birds across vast geographic regions and caused wildlife deaths in some of the world's most biodiverse ecosystems. Hundreds of millions of poultry have died or been culled, affecting global food security in some of the world's poorest regions. Numerous mammalian species, including sea lions and fur animals, have been infected. Outbreaks in dairy cows in the United States have been occurring for months, seemingly unchecked in most affected states. Why is there not a greater sense of urgency to control these infections?

Date Created: 20240711 Date Completed: 20240711 Latest Revision: 20240712

20240713

10.1126/science.adr5866

38991057