Remission of hypersensitivity pneumonitis after allogeneic hematopoietic stem cell transplantation.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101581124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-5353 (Electronic) Linking ISSN: 22125345 NLM ISO Abbreviation: Respir Investig Subsets: MEDLINE
    • Publication Information:
      Original Publication: Amsterdam : Elsevier
    • Subject Terms:
      Hematopoietic Stem Cell Transplantation*/adverse effects ; Alveolitis, Extrinsic Allergic*/etiology ; Alveolitis, Extrinsic Allergic*/diagnosis ; Alveolitis, Extrinsic Allergic*/therapy ; Myelodysplastic Syndromes*/therapy ; Transplantation, Homologous*; Humans ; Male ; Middle Aged ; Remission Induction ; Tomography, X-Ray Computed ; Prednisolone/administration & dosage
    • Abstract:
      A 50-year-old man was diagnosed with hypersensitivity pneumonitis caused by the environment of his bar owing to worsening symptoms, laboratory test results, and computed tomography images after an environmental inhalation challenge test. His hypersensitivity pneumonitis exacerbated despite receiving prednisolone 20 mg/day. The patient underwent allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte antigen-matched unrelated donor for myelodysplastic syndrome. No exacerbation of hypersensitivity pneumonitis was observed after HSCT. An environmental inhalation challenge test involving exposure to his bar confirmed the remission of hypersensitivity pneumonitis after HSCT. This case demonstrates that hypersensitivity pneumonitis can be remitted by HSCT.
      Competing Interests: Declaration of competing interest The authors have no conflicts of interest.
      (Copyright © 2024. Published by Elsevier B.V.)
    • Contributed Indexing:
      Keywords: Allogeneic hematopoietic stem cell transplantation; Environmental inhalation challenge test; Hypersensitivity pneumonitis; Myelodysplastic syndrome
    • Accession Number:
      9PHQ9Y1OLM (Prednisolone)
    • Publication Date:
      Date Created: 20240703 Date Completed: 20240825 Latest Revision: 20240825
    • Publication Date:
      20240826
    • Accession Number:
      10.1016/j.resinv.2024.06.007
    • Accession Number:
      38959673