Novel diacylglycerol oil-based nanostructured lipid carriers improves the stability and digestibility of lycopene.

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  • Additional Information
    • Source:
      Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE
    • Publication Information:
      Publication: Barking : Elsevier Applied Science Publishers
      Original Publication: Barking, Eng., Applied Science Publishers.
    • Subject Terms:
      Diglycerides*/chemistry ; Lycopene*/chemistry ; Nanostructures*/chemistry ; Digestion* ; Lipids*/chemistry; Drug Carriers/chemistry ; Drug Stability ; Humans
    • Abstract:
      Diacylglycerol (DAG) has garnered attention for its safe and nutritious qualities, and its utilization in emulsion systems to encapsulate hydrophobic bioactives is anticipated to enhance their bioaccessibility. Thus, this study aimed to evaluate the influence of DAG oil as a carrier on the stability and digestive characteristics of nanostructured lipid carriers (NLCs) containing lycopene (LYC). The results indicated that DAG oil demonstrated superior storage and heating stability in comparison to triacylglycerol (TAG) oil. Furthermore, NLCs formulated with DAG oil exhibited a faster rate of lipolysis (>76.3%) and higher loading capacity (1.48%), resulting in an approximate 11% enhancement in the bioaccessibility of LYC (reaching up to 31.4%). DAG oils show considerable potential for enhancing and prolonging the properties and bioactivity of NLC carriers, thereby boosting bioaccessibility. The incorporation of DAG oil in food systems holds promise for enriching their functionality over traditional TAG oil.
      Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Bing Shao reports financial support was provided by Guangdong Provincial Key R&D Programme. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
      (Copyright © 2023. Published by Elsevier Ltd.)
    • Contributed Indexing:
      Keywords: Bioaccessibility; Heating stability; In vitro digestion; LYC release; Soybean oil; Storage stability
    • Accession Number:
      0 (Diglycerides)
      SB0N2N0WV6 (Lycopene)
      0 (Lipids)
      0 (Drug Carriers)
    • Publication Date:
      Date Created: 20240629 Date Completed: 20240824 Latest Revision: 20240824
    • Publication Date:
      20240826
    • Accession Number:
      10.1016/j.foodchem.2024.140219
    • Accession Number:
      38943966