Pupillary constriction on stimulation of the parietal cortex-A novel finding.

Publisher: Wiley Country of Publication: United States NLM ID: 100891853 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6945 (Electronic) Linking ISSN: 12949361 NLM ISO Abbreviation: Epileptic Disord Subsets: MEDLINE

Publication: 2023- : [Hoboken] : Wiley
Original Publication: Montrouge, France : John Libbey Eurotext

Parietal Lobe*/physiopathology ; Electroencephalography* ; Drug Resistant Epilepsy*/physiopathology ; Drug Resistant Epilepsy*/surgery; Humans ; Epilepsies, Partial/physiopathology ; Electric Stimulation ; Male ; Adult ; Female ; Pupil Disorders/physiopathology ; Pupil Disorders/etiology

Pupillary changes can be an important semiologic feature in focal epilepsy. Though the subcortical networks involving pupillomotor function have been described, cortical generators of pupillary dilation and constriction in humans are not well known. In this report, we describe a case of pupillary constriction occurring during seizures in a patient with drug resistant focal epilepsy. On stereoelectroencephalography, onset was noted within the posterior segment of the right intraparietal sulcus and direct cortical electrical stimulation of these electrode contacts reproduced pupillary constriction associated with habitual seizures. This is the first case report to describe ictal pupillary constriction during SEEG with confirmation of the cortical localization by direct cortical electrical stimulation. The posterior segment of the right intraparietal sulcus localization of pupillary constriction may aid in surgical evaluation patients with drug resistant focal epilepsy.
(© 2024 International League Against Epilepsy.)

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Keywords: autonomic seizure; central autonomic network; cortical stimulation; ictal miosis; posterior cortex parietal; pupillary constriction; stereoelectroencephalography

Date Created: 20240629 Date Completed: 20241012 Latest Revision: 20241012

20241013

10.1002/epd2.20252

38943530