Investigation of Post-Transplant Mental Well-Being in Liver Transplant Recipients with Hepatic Encephalopathy.

Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE

Original Publication: Basel, Switzerland : MDPI AG, [2012]-

Objective : In this study, we aimed to examine the healing trend of hepatic encephalopathy after transplantation surgery in patients with liver failure. Method : We conducted this descriptive and cross-sectional study with the participation of liver transplant recipients. A personal information form, the West Haven Criteria (WHC), the Warwick-Edinburgh Mental Well-Being Scale (WEMWBS), and the Richmond Agitation Sedation Scale (RASS) were used for data collection. The data were analyzed using Chi-squared tests, ANOVA, and paired-samples t -tests. Results : As time progressed after liver transplantation, hepatic encephalopathy stages regressed ( p < 0.01). We found that liver transplant recipients with end-stage hepatic encephalopathy were mostly within the first 6 months after transplantation, while patients with first-stage hepatic encephalopathy had received liver transplants more than 2 years ago ( p < 0.01). Conclusions : The results of our study revealed that hepatic encephalopathy stages regressed after transplantation, but there was no complete recovery. This highlights the need to develop new treatment strategies other than liver transplantation for the treatment of hepatic encephalopathy.

Hepatology. 2007 Mar;45(3):797-805. (PMID: 17326206)
Neurocrit Care. 2008;8(2):253-8. (PMID: 17928960)
Front Neurol. 2012 Jun 19;3:101. (PMID: 22723791)
Transplant Proc. 2006 Jun;38(5):1407-10. (PMID: 16797318)
Transplant Proc. 2013 Oct;45(8):3069-71. (PMID: 24157038)
Am J Gastroenterol. 2020 May;115(5):783-785. (PMID: 31449156)
Hepatology. 2014 Aug;60(2):715-35. (PMID: 25042402)
Am J Transplant. 2017 Jul;17(7):1833-1842. (PMID: 28097804)
Transplant Proc. 2014 Apr;46(3):712-5. (PMID: 24767331)
Clin Gastroenterol Hepatol. 2015 Nov;13(12):2048-61. (PMID: 26164219)
J Am Geriatr Soc. 2006 Mar;54(3):479-84. (PMID: 16551316)
Intensive Care Med. 2008 Mar;34(3):437-46. (PMID: 18087692)
J Clin Transl Hepatol. 2017 Jun 28;5(2):142-151. (PMID: 28660152)
J Hepatol. 2013 Apr;58(4):698-705. (PMID: 23220368)
Clin Gastroenterol Hepatol. 2016 Jun;14(6):903-906.e1. (PMID: 26707685)
Liver Transpl. 2009 Jan;15(1):111-4. (PMID: 19109845)
Proc (Bayl Univ Med Cent). 2020 Jan 9;33(2):256-257. (PMID: 32313479)
Hepatology. 2001 Feb;33(2):464-70. (PMID: 11172350)
Aliment Pharmacol Ther. 2011 Apr;33(7):739-47. (PMID: 21306407)
Intensive Care Med. 2008 Oct;34(10):1907-15. (PMID: 18563387)
J Hepatol. 2002 Jan;36(1):141-2. (PMID: 11804679)
J Emerg Trauma Shock. 2017 Jan-Mar;10(1):37-46. (PMID: 28243012)
Neuroradiology. 1998 Dec;40(12):793-6. (PMID: 9877133)
Transplantation. 2009 Mar 15;87(5):734-9. (PMID: 19295319)
Drugs. 2019 Feb;79(Suppl 1):5-9. (PMID: 30706420)
Hepatology. 2000 Apr;31(4):864-71. (PMID: 10733541)
Clin Transplant. 2010 Jan-Feb;24(1):91-7. (PMID: 19925461)
J Hepatol. 2001 May;34(5):768-73. (PMID: 11434627)
Liver Transpl. 2006 Apr;12(4):614-20. (PMID: 16555319)
Hepatology. 2014 Mar;59(3):1073-83. (PMID: 23847109)
Health Qual Life Outcomes. 2007 Nov 27;5:63. (PMID: 18042300)
J Hepatol. 2022 Sep;77(3):807-824. (PMID: 35724930)
Cent Afr J Med. 1967 Jun;13(6):147. (PMID: 6077488)
J Clin Exp Hepatol. 2015 Mar;5(Suppl 1):S82-7. (PMID: 26041964)
Transplant Proc. 2012 Mar;44(2):421-3. (PMID: 22410033)
Liver Transpl. 2009 Feb;15(2):184-92. (PMID: 19177446)
J Hepatol. 2011 May;54(5):1030-40. (PMID: 21145874)
Liver Transpl. 2016 Jun;22(6):732-42. (PMID: 27028317)
Am J Gastroenterol. 2023 Jan 1;118(1):10-13. (PMID: 36001400)
J Hepatol. 2015 Feb;62(2):437-47. (PMID: 25218789)

Keywords: hepatic encephalopathy; liver transplantation; long-term healing

Date Created: 20240619 Latest Revision: 20240620

20240620

PMC11172876

10.3390/jcm13113249

38892960