Uveitis-Glaucoma-Hyphema Syndrome From Subtle Malposition of a Hydrus Microstent.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Author(s): Polski A;Polski A; Long T; Stagg BC; Wirostko B
  • Source:
    Journal of glaucoma [J Glaucoma] 2024 Nov 01; Vol. 33 (11), pp. e92-e96. Date of Electronic Publication: 2024 Jun 18.
  • Publication Type:
    Case Reports; Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 9300903 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-481X (Electronic) Linking ISSN: 10570829 NLM ISO Abbreviation: J Glaucoma Subsets: MEDLINE
    • Publication Information:
      Publication: <2015- > : Philadelphia, PA : Wolters Kluwer Health, Inc.
      Original Publication: New York, N.Y. : Raven Press, c1992-
    • Subject Terms:
      Hyphema*/etiology ; Hyphema*/diagnosis ; Glaucoma Drainage Implants*/adverse effects ; Intraocular Pressure*/physiology ; Stents*/adverse effects ; Device Removal* ; Glaucoma*/surgery ; Glaucoma*/etiology ; Uveitis*/diagnosis ; Uveitis*/etiology; Humans ; Syndrome ; Female ; Male ; Middle Aged
    • Abstract:
      Uveitis-glaucoma-hyphema (UGH) syndrome is a rare condition characterized by intraocular inflammation, elevated intraocular pressure, and recurrent hyphema. Although UGH syndrome is typically caused by chafing between an intraocular lens and the iris or ciliary body, microinvasive glaucoma devices are becoming increasingly recognized as potential causes of recurrent intraocular inflammation. Herein, we discuss a case of UGH syndrome due to the subtle malposition of a Hydrus microstent that ultimately required surgical removal to manage. This represents the first case of Hydrus-related UGH syndrome to include high-quality anterior segment imaging, which led us to suspect Hydrus-iris contact and supported the decision to proceed with microstent explantation.
      Competing Interests: Disclosure: The authors declare no conflict of interest.
      (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
    • References:
      Ellingson FT. The uveitis-glaucoma-hyphema syndrome associated with the Mark VIII anterior chamber lens implant. J Am Intraocul Implant Soc. 1978;4:50–53.
      Apple DJ, Mamalis N, Loftfield K, et al. Complications of intraocular lenses. A historical and histopathological review. Surv Ophthalmol. 1984;29:1–54.
      Lin CJ, Tan CY, Lin SY, et al. Uveitis-glaucoma-hyphema syndrome caused by posterior chamber intraocular lens—a rare complication in pediatric cataract surgery. Ann Ophthalmol (Skokie). 2008;40:183–184.
      Chang DF, Masket S, Miller KM, et al. Complications of sulcus placement of single-piece acrylic intraocular lenses: recommendations for backup IOL implantation following posterior capsule rupture. J Cataract Refract Surg. 2009;35:1445–1458.
      Foroozan R, Tabas JG, Moster ML. Recurrent microhyphema despite intracapsular fixation of a posterior chamber intraocular lens. J Cataract Refract Surg. 2003;29:1632–1635.
      Alfaro-Juárez A, Vital-Berral C, Sánchez-Vicente JL, et al. Uveitis-glaucoma-hyphema syndrome associated with recurrent vitreous hemorrhage. Arch Soc Esp Oftalmol. 2015;90:392–394.
      Cheung AY, Price JM, Heidemann DG, et al. Uveitis-glaucoma-hyphema syndrome caused by dislocated Cionni endocapsular tension ring. Can J Ophthalmol. 2018;53:e213–e214.
      Hou A, Hasbrook M, Crandall D. A case of uveitis-hyphema-glaucoma syndrome due to EX-PRESS glaucoma filtration device implantation. J Glaucoma. 2019;28:e159–e161.
      Siedlecki A, Kinariwala B, Sieminski S. Uveitis-glaucoma-hyphema syndrome following iStent implantation. Case Rep Ophthalmol. 2022;13:82–88.
      Capitena Young CE, St Peter DM, Ertel MK, et al. Hydrus Microstent malposition with uveitis-glaucoma-hyphema syndrome. Am J Ophthalmol Case Rep. 2022;25:101405.
      Kaplan TM, Sit AJ. A case of uveitis-glaucoma-hyphema syndrome related to a hydrus microstent. J Glaucoma. 2023;33:51–54.
      Richter GM, Coleman AL. Minimally invasive glaucoma surgery: current status and future prospects. Clin Ophthalmol. 2016;10:189–206.
      Ahmed IIK, De Francesco T, Rhee D, et al. Long-term outcomes from the HORIZON randomized trial for a Schlemm’s Canal Microstent in combination cataract and glaucoma surgery. Ophthalmology. 2022;129:742–751.
      Piette S, Canlas OA, Tran HV, et al. Ultrasound biomicroscopy in uveitis-glaucoma-hyphema syndrome. Am J Ophthalmol. 2002;133:839–841.
      Izatt JA, Hee MR, Swanson EA, et al. Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography. Arch Ophthalmol. 1994;112:1584–1589.
    • Publication Date:
      Date Created: 20240617 Date Completed: 20241104 Latest Revision: 20241218
    • Publication Date:
      20241218
    • Accession Number:
      PMC11556866
    • Accession Number:
      10.1097/IJG.0000000000002451
    • Accession Number:
      38884627