Comparative analysis of the efficacy and safety of different methods for injecting polidocanol in the treatment of venous malformations.

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  • Additional Information
    • Source:
      Publisher: Sage Country of Publication: England NLM ID: 9012921 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-1125 (Electronic) Linking ISSN: 02683555 NLM ISO Abbreviation: Phlebology Subsets: MEDLINE
    • Publication Information:
      Publication: Oct. 2012- : London : Sage
      Original Publication: [Houndmills, Basingstoke, Hampshire, UK] : Scientific & Medical, Macmillan Press,
    • Subject Terms:
      Polidocanol*/administration & dosage ; Vascular Malformations*/drug therapy ; Vascular Malformations*/diagnostic imaging ; Sclerosing Solutions*/administration & dosage ; Sclerosing Solutions*/adverse effects; Humans ; Female ; Male ; Adult ; Retrospective Studies ; Adolescent ; Child ; Middle Aged ; Sclerotherapy/adverse effects ; Sclerotherapy/methods ; Angiography, Digital Subtraction ; Veins/diagnostic imaging ; Veins/abnormalities ; Treatment Outcome ; Child, Preschool
    • Abstract:
      Objective: To compare and analyze the efficacy and safety of different methods for injecting polidocanol in the treatment of venous malformations.
      Methods: The medical records of patients with venous malformations in our hospital from April 2021 to April 2023 were analyzed retrospectively, and they were divided into control group ( n = 38) and observation group ( n = 20) according to different treatment methods. Control group was injected with polidocanol under ultrasound guidance, while observation group was injected with polidocanol under digital subtraction angiography (DSA) monitoring. Therapeutic effects of observation group and control group after 3-6 months of treatment were compared and analyzed, and complications that can be used to reflect the safety of treatment in two groups were collected and recorded.
      Results: After treatment, the total effective rates of observation group and control group were 97.37% (37/38) and 75.00% (15/20) respectively, with significant differences (both p < .05). After 3-6 months of treatment, 13 complications occurred in observation group, while 16 occurred in control group. The number of complications in observation group was 6, with an incidence rate of 15.78%; while that in control group was 9, with an incidence rate of 45.00%, with a significant difference ( p < .05). There were no significant differences among other baseline data, age and complications between two groups (all p > .05).
      Conclusion: Injection of polidocanol in patients with venous malformations under DSA monitoring was more effective and safer.
      Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
    • Contributed Indexing:
      Keywords: Venous malformations; clinical efficacy; digital subtraction angiography; safety; ultrasound
    • Accession Number:
      0AWH8BFG9A (Polidocanol)
      0 (Sclerosing Solutions)
    • Publication Date:
      Date Created: 20240615 Date Completed: 20241018 Latest Revision: 20241018
    • Publication Date:
      20241018
    • Accession Number:
      10.1177/02683555241263228
    • Accession Number:
      38877884