Effect of ph on migration patterns and degradation pathways of sulfamethazine in soil systems.

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  • Additional Information
    • Source:
      Publisher: Taylor & Francis Country of Publication: England NLM ID: 7607167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-4109 (Electronic) Linking ISSN: 03601234 NLM ISO Abbreviation: J Environ Sci Health B Subsets: MEDLINE
    • Publication Information:
      Publication: 2005- : Abingdon, Oxford : Taylor & Francis
      Original Publication: New York, Dekker.
    • Subject Terms:
      Hydrogen-Ion Concentration* ; Sulfamethazine*/analysis ; Sulfamethazine*/chemistry ; Soil Pollutants*/analysis ; Soil Pollutants*/chemistry ; Anti-Infective Agents*/analysis ; Anti-Infective Agents*/chemistry; Chromatography, Liquid ; Salinity
    • Abstract:
      Sulfonamide antibiotics (SAs) are widely used antimicrobial agents in livestock and aquaculture, and most of them entering the animal's body will be released into the environment as prodrugs or metabolites, which ultimately affect human health through the food chain. Both acid deposition and salinization of soil may have an impact on the migration and degradation of antibiotics. Sulfamethazine (SM2), a frequently detected compound in agricultural soils, has a migration and transformation process in the environment that is closely dependent on environmental pH. Nevertheless, scarcely any studies have been conducted on the effect of soil pH changes on the environmental behavior of sulfamethazine. We analyzed the migration and degradation mechanisms of SM2 using simulation experiments and ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) techniques. The results showed that acidic conditions limited the vertical migration of sulfadimidine, and SM2 underwent different reaction processes under different pH conditions, including S-C bond breaking, S-N bond hydrolysis, demethylation, six-membered heterocyclic addition, methyl hydroxylation and ring opening. The study of the migration pattern and degradation mechanism of SM2 under different pH conditions can provide a solid theoretical basis for assessing the pollution risk of sulfamethazine degradation products under acid rain and saline conditions, and provide a guideline for remediation of antibiotic contamination, so as to better prevent, control and protect groundwater resources.
    • Contributed Indexing:
      Keywords: Sulfamethazine; degradation pathway; degradation product; migration mechanism; soil
    • Accession Number:
      48U51W007F (Sulfamethazine)
      0 (Soil Pollutants)
      0 (Anti-Infective Agents)
    • Publication Date:
      Date Created: 20240607 Date Completed: 20240618 Latest Revision: 20240624
    • Publication Date:
      20240625
    • Accession Number:
      10.1080/03601234.2024.2363580
    • Accession Number:
      38847499