The mediating role of meaning in life between experiential avoidance and death anxiety among cancer patients: a cross-sectional study.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BioMed Central, [2001-
    • Subject Terms:
    • Abstract:
      Background: Death anxiety is thought to cause a range of mental disorders among cancer patients, which may affect their mental health and even quality of life. This study sought to investigate experiential avoidance, meaning in life, and death anxiety among Chinese cancer patients and then explore the relationship between these 3 variables.
      Methods: A total of 300 cancer patients recruited from a tertiary cancer hospital participated in this study from October to December 2021. A cross-sectional survey was conducted using a demographic and clinical characteristics questionnaire, the Acceptance and Action Questionnaire II, the Meaning in Life Questionnaire, and Templer's Death Anxiety Scale. Correlation analysis, hierarchical regression analysis, and mediating effect analysis were used to analyze the relationship among experiential avoidance, meaning in life (including 2 dimensions: presence of meaning and search for meaning), and death anxiety.
      Results: A total of 315 questionnaires were distributed, and 300 valid questionnaires were returned, resulting in a valid response rate of 95.2%. Experiential avoidance (r = 0.552, p < 0.01) was moderately positively correlated with death anxiety. Presence of meaning (r = - 0.400, p < 0.01) was moderately negatively correlated with death anxiety, while search for meaning (r = - 0.151, p < 0.01) was weakly negatively correlated with death anxiety. Regression analysis showed that experiential avoidance (β = 0.464) and presence of meaning (β = -0.228) were predictors of death anxiety. Mediating effect analysis revealed that presence of meaning either completely or partially mediated the effect of experiential avoidance and death anxiety, and the indirect effect accounted for 14.52% of the total effect.
      Conclusion: Overall, experiential avoidance predicts death anxiety in cancer patients, and meaning in life can mediate this effect. The results of this study provide a new path for studying the mechanism of death anxiety and suggest a more positive and promising strategy for its management.
      (© 2024. The Author(s).)
    • References:
      Psychooncology. 2018 Nov;27(11):2559-2565. (PMID: 29843188)
      J Pain Symptom Manage. 2021 Jan;61(1):32-41.e2. (PMID: 32711122)
      Asia Pac J Oncol Nurs. 2016 Apr-Jun;3(2):183-191. (PMID: 27981157)
      Int J Environ Res Public Health. 2019 Sep 28;16(19):. (PMID: 31569371)
      Behav Pharmacol. 2019 Apr;30(2 and 3-Spec Issue):220-228. (PMID: 30883392)
      Psychooncology. 2017 Apr;26(4):469-475. (PMID: 27228257)
      J Consult Clin Psychol. 1996 Dec;64(6):1152-68. (PMID: 8991302)
      Eur J Cancer Care (Engl). 2015;24(1):15-27. (PMID: 25100576)
      Psychol Rep. 2017 Jun;120(3):383-390. (PMID: 28558607)
      Clin Psychol Rev. 2014 Nov;34(7):580-93. (PMID: 25306232)
      J Anxiety Disord. 2019 May;64:9-15. (PMID: 30852258)
      J Pers Soc Psychol. 2014 Apr;106(4):610-23. (PMID: 24660992)
      J Gen Psychol. 1970 Apr;82(2d Half):165-77. (PMID: 4394812)
      Behav Ther. 2011 Dec;42(4):676-88. (PMID: 22035996)
      Turk J Emerg Med. 2018 Aug 07;18(3):91-93. (PMID: 30191186)
      Psychol Health Med. 2022 Apr;27(4):803-814. (PMID: 33487048)
      J Pers Soc Psychol. 1986 Dec;51(6):1173-82. (PMID: 3806354)
      BMC Geriatr. 2019 Nov 12;19(1):308. (PMID: 31718561)
      Psicothema. 2016 Aug;28(3):266-71. (PMID: 27448259)
      BMJ Support Palliat Care. 2018 Mar;8(1):61-63. (PMID: 28611157)
      Res Theory Nurs Pract. 2009;23(1):23-41. (PMID: 19418886)
      BMJ Support Palliat Care. 2015 Dec;5(4):373-80. (PMID: 24644177)
      Eur J Oncol Nurs. 2020 Oct;48:101803. (PMID: 32836000)
      Behav Res Ther. 2006 Jan;44(1):1-25. (PMID: 16300724)
      Int J Palliat Nurs. 2006 Sep;12(9):410-3. (PMID: 17077799)
      Psychol Psychother. 2020 Sep;93(3):456-473. (PMID: 30994261)
      Psychol Rev. 1999 Oct;106(4):835-45. (PMID: 10560330)
    • Grant Information:
      82103026 National Natural Science Foundation of China; 2020SK51105 Science and Technology Innovation Program of Hunan Province, China
    • Contributed Indexing:
      Keywords: Cancer patients; Death anxiety; Experiential avoidance; Meaning in life; Mediation effect
    • Publication Date:
      Date Created: 20240531 Date Completed: 20240601 Latest Revision: 20240603
    • Publication Date:
      20240603
    • Accession Number:
      PMC11141075
    • Accession Number:
      10.1186/s12885-024-12433-0
    • Accession Number:
      38822257