Cephaliverins A-D, four new lignans from Cephalotaxus oliveri Mast.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE
    • Publication Information:
      Publication: 1999- : [Amsterdam] : Elsevier
      Original Publication: Milano : Inverni & Della Beffa S.p.A.
    • Subject Terms:
      Lignans*/isolation & purification ; Lignans*/pharmacology ; Lignans*/chemistry ; Cephalotaxus*/chemistry ; Antineoplastic Agents, Phytogenic*/pharmacology ; Antineoplastic Agents, Phytogenic*/isolation & purification; Humans ; Molecular Structure ; Phytochemicals/pharmacology ; Phytochemicals/isolation & purification ; Hep G2 Cells ; A549 Cells ; China
    • Abstract:
      Four new lignans named cephaliverins A-D (1-4), along with seven known analogues (5-11), were isolated from Cephalotaxus oliveri Mast. Their structures were elucidated on the basis of HR-ESI-MS and NMR analyses, and their absolute configurations were determined by ECD comparison. Cephaliverin A (1), herpetotriol (5) and hedyotol A (6) exhibited moderate antitumor activity against HepG2 and A549 cell lines.
      Competing Interests: Declaration of competing interest The authors declare that they have no conflicts of interest.
      (Copyright © 2024. Published by Elsevier B.V.)
    • Contributed Indexing:
      Keywords: Antitumor activity; Cephalotaxaceae; Cephalotaxus oliveri Mast.; Lignans
    • Accession Number:
      0 (Lignans)
      0 (Antineoplastic Agents, Phytogenic)
      0 (Phytochemicals)
    • Publication Date:
      Date Created: 20240527 Date Completed: 20240809 Latest Revision: 20240809
    • Publication Date:
      20240812
    • Accession Number:
      10.1016/j.fitote.2024.106040
    • Accession Number:
      38801892