Trajectories of patient-reported outcomes after oesophageal cancer surgery - A population-based study.

Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE

Publication: Oxford : Elsevier Science Ltd
Original Publication: Oxford ; New York : Pergamon Press, c1990-

Esophageal Neoplasms*/surgery ; Patient Reported Outcome Measures* ; Quality of Life*; Humans ; Male ; Female ; Aged ; Middle Aged ; Sweden/epidemiology ; Esophagectomy/adverse effects ; Deglutition Disorders/etiology ; Deglutition Disorders/epidemiology ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Smoking/adverse effects ; Smoking/epidemiology ; Exercise

Background: This study aimed to investigate the trajectories of patient-reported outcomes for individuals who have undergone surgery for oesophageal cancer over a five-year post-surgical period, and to identify modifiable factors that contribute to a decline in quality of life.
Methods: Patients who underwent resection in Sweden between 2013 and 2020 were included. Data were collected at one-year post-surgery and at regular pre-determined intervals during the five-year post-surgical period. Latent class analysis and logistic regression models were used to identify symptom trajectories and determine their association with lifestyle factors, respectively.
Results: This study included 408 patients, and the majority experienced consistent symptom burdens during the five-year post-surgery period. Current smokers had a higher risk of belonging to the severe dysphagia, severe eating restriction, and severe reflux trajectory. Physically active patients were less likely to belong to the severe dysphagia, severe eating restriction, and severe pain and discomfort trajectory. Patients with a stable weight were less likely to belong to the severe eating restriction and to the recovering body image trajectory.
Conclusions: Patients who are smokers, have a low level of physical activity, and experience weight loss need further attention and individual support to mitigate long-term symptom burden.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Keywords: Oesophagal neoplasm; Signs and symptoms; Stomach neoplasm

Date Created: 20240526 Date Completed: 20240615 Latest Revision: 20240615

20240616

10.1016/j.ejca.2024.114133

38797039