Effects of bamboo leaf flavonoids on growth performance, antioxidants, immune function, intestinal morphology, and cecal microbiota in broilers.

Publisher: John Wiley & Sons Country of Publication: England NLM ID: 0376334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0010 (Electronic) Linking ISSN: 00225142 NLM ISO Abbreviation: J Sci Food Agric Subsets: MEDLINE

Publication: <2005-> : Chichester, West Sussex : John Wiley & Sons
Original Publication: London, Society of Chemical Industry.

Chickens*/growth & development ; Chickens*/immunology ; Chickens*/microbiology ; Chickens*/metabolism ; Antioxidants*/metabolism ; Antioxidants*/pharmacology ; Antioxidants*/administration & dosage ; Gastrointestinal Microbiome*/drug effects ; Plant Leaves*/chemistry ; Flavonoids*/administration & dosage ; Flavonoids*/pharmacology ; Cecum*/microbiology ; Cecum*/metabolism ; Cecum*/drug effects ; Animal Feed*/analysis ; Intestines*/drug effects ; Intestines*/microbiology ; Intestines*/immunology; Animals ; Dietary Supplements/analysis ; Plant Extracts/administration & dosage ; Plant Extracts/pharmacology ; Male ; Bacteria/classification ; Bacteria/drug effects ; Bacteria/isolation & purification ; Bacteria/genetics ; Immunoglobulin M/blood ; Immunoglobulin A/blood ; Tumor Necrosis Factor-alpha/metabolism ; Tumor Necrosis Factor-alpha/blood ; Bambusa/chemistry ; Interleukin-10/blood ; Interleukin-10/metabolism ; Sasa/chemistry

Background: Bamboo leaf flavonoids (BLF) are the main bioactive ingredients in bamboo leaves. They have antioxidant, anti-inflammatory, antibacterial, and other effects. In this study, the effects of dietary BLF on growth performance, immune response, antioxidant capacity, and intestinal microbiota of broilers were investigated. A total of 288 broilers were divided into three groups with eight replicates and 12 birds in each replicate. Broilers were fed a basic diet or the basic diet supplemented with 1000 or 2000 mg kg ^-1 BLF for 56 days.
Results: The results showed that supplementation of BLF increased body weight (BW) and average daily weight gain (ADG), and reduced average daily feed intake (ADFI) (P < 0.05). The serum immunoglobulin A (IgA), immunoglobulin M (IgM), and interleukin 10 (IL-10) content of broilers in the BLF1000 group was increased and the interleukin 1β (IL-1β) and tumor necrosis factor-α (TNF-α) content was decreased (P < 0.05). The levels of IgM and IL-10 in jejunum mucosa were found to be enhanced by BLF (P < 0.05). The BLF1000 group exhibited a significant reduction in the concentration of TNF-α (P < 0.05). Serum and jejunum mucosa total antioxidant capacity (T-AOC) levels in the BLF1000 group were increased (P < 0.05). The serum catalase (CAT) and glutathione peroxidase (GSH-Px) effects of the BLF1000 group and serum CAT effects of BLF2000 group were increased (P < 0.05). The CON group demonstrated a lower relative abundance of Christensenellaceae_R-7_group and Oscillibacter than the BLF group (P < 0.05).
Conclusion: Dietary BLF inclusion enhanced the growth performance, immune, and antioxidant functions, improved the intestinal morphology, and ameliorated the intestinal microflora structure in broiler. Adding 1000 mg kg ^-1 BLF to the broiler diet can be considered as an effective growth promoter. © 2024 Society of Chemical Industry.
(© 2024 Society of Chemical Industry.)

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32202687 The National Natural Science Foundation of China; 2022C02059 Zhejiang Provincial Key R&D Program of China; 2021Y30004 Zhejiang Provincial Key Agricultural Research Institute of Green Animal Health Products Project

Keywords: antioxidant function; bamboo leaf flavonoid; broiler; growth performance; intestinal microbiota

0 (Antioxidants)
0 (Flavonoids)
0 (Plant Extracts)
0 (Immunoglobulin M)
0 (Immunoglobulin A)
0 (Tumor Necrosis Factor-alpha)
130068-27-8 (Interleukin-10)

Date Created: 20240521 Date Completed: 20240806 Latest Revision: 20240806

20240806

10.1002/jsfa.13602

38770921