Association between egg consumption and mortality risk in United States adults with established coronary heart disease or stroke: A cohort study using data from NHANES 1999-2018.

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  • Additional Information
    • Source:
      Publisher: Elsevier Biomedical Press Country of Publication: Netherlands NLM ID: 8214379 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6976 (Electronic) Linking ISSN: 01674943 NLM ISO Abbreviation: Arch Gerontol Geriatr Subsets: MEDLINE
    • Publication Information:
      Original Publication: Amsterdam : Elsevier Biomedical Press, c1982-
    • Subject Terms:
      Eggs* ; Nutrition Surveys* ; Coronary Disease*/mortality ; Coronary Disease*/epidemiology ; Stroke*/mortality ; Stroke*/epidemiology; Humans ; Female ; Male ; United States/epidemiology ; Middle Aged ; Adult ; Aged ; Cohort Studies ; Diet/statistics & numerical data ; Risk Factors ; Proportional Hazards Models
    • Abstract:
      Background: To investigate the relationship between egg consumption and mortality in individuals with pre-existing coronary heart disease or stroke.
      Methods: This study utilized data from the National Health and Nutrition Examination Survey conducted between 1999 and 2018. Egg consumption was evaluated through 24 h dietary recalls at baseline. Mortality status was tracked until December 31, 2019. Survey-weighted Cox proportional hazards models were utilized.
      Results: The study involved 3,975 participants aged 20 years or older with a median follow-up of 89.00 months. A total of 1,675 individuals died during follow-up. Compared to individuals who did not consume eggs, the consumption of 0-50 g/day (hazard ratio [HR] = 1.033, 95% confidence interval [CI] =0.878-1.214) was not found to have a significant association with all-cause mortality. However, consuming 50-100 g/day (HR = 1.281, 95% CI = 1.004-1.635) and >100 g/day (HR = 1.312, 95% CI =1.036-1.661) exhibited a significant association with an increased risk of all-cause mortality. We identified a non-liner relationship between egg consumption and cardiovascular mortality, where the risk was found to be lowest at an intake of about 50 g/day. For individuals consuming more than 50 g/day, each additional 50 g increment in egg consumption was significantly linked to an elevated risk of cardiovascular mortality (HR = 1.276, 95% CI = 1.009-1.614).
      Conclusion: In U.S. adults with pre-existing cardiovascular disease, a significant positive association was found between consuming over 50 g of eggs per day and the risk of mortality, highlighting the importance of moderate intake.
      Competing Interests: Declaration of competing interest All authors declare no potential conflict of interest.
      (Copyright © 2024 Elsevier B.V. All rights reserved.)
    • Contributed Indexing:
      Keywords: Cardiovascular disease; Coronary heart disease; Egg consumption; Mortality; Stroke
    • Publication Date:
      Date Created: 20240511 Date Completed: 20240615 Latest Revision: 20240924
    • Publication Date:
      20240924
    • Accession Number:
      10.1016/j.archger.2024.105475
    • Accession Number:
      38733921