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Protocol for a systematic review of the application of the kidney failure risk equation and Oxford classification in estimating prognosis in IgA nephropathy.
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- Author(s): Toal M;Toal M;Toal M; Fergie R; Fergie R; Fergie R; Quinn M; Quinn M; Hill C; Hill C; O'Neill C; O'Neill C; Maxwell AP; Maxwell AP
- Source:
Systematic reviews [Syst Rev] 2024 May 04; Vol. 13 (1), pp. 122. Date of Electronic Publication: 2024 May 04.- Publication Type:
Journal Article; Research Support, Non-U.S. Gov't- Language:
English - Source:
- Additional Information
- Source: Publisher: BioMed Central Country of Publication: England NLM ID: 101580575 Publication Model: Electronic Cited Medium: Internet ISSN: 2046-4053 (Electronic) Linking ISSN: 20464053 NLM ISO Abbreviation: Syst Rev Subsets: MEDLINE
- Publication Information: Original Publication: London : BioMed Central
- Subject Terms: Glomerulonephritis, IGA*/classification ; Glomerulonephritis, IGA*/complications ; Glomerulonephritis, IGA*/pathology ; Systematic Reviews as Topic* ; Disease Progression* ; Kidney Failure, Chronic*; Humans ; Prognosis ; Risk Assessment/methods ; Renal Insufficiency, Chronic/classification ; Renal Insufficiency, Chronic/complications ; Biopsy
- Abstract: Background: IgA nephropathy (IgAN) is a common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD). Outcomes are highly variable and predicting risk of disease progression at an individual level is challenging. Accurate risk stratification is important to identify individuals most likely to benefit from treatment. The Kidney Failure Risk Equation (KFRE) has been extensively validated in CKD populations and predicts the risk of ESRD at 2 and 5 years using non-invasive tests; however, its predictive performance in IgAN is unknown. The Oxford classification (OC) describes pathological features demonstrated on renal biopsy that are associated with adverse clinical outcomes that may also inform prognosis. The objective of this systematic review is to compare the KFRE with the OC in determining prognosis in IgAN.
Methods: A systematic review will be conducted and reported in line with PRISMA guidelines (PRISMA-P checklist attached as Additional file 1). Inclusion criteria will be cohort studies that apply the KFRE or OC to determine the risk of CKD progression or ESRD in individuals with IgAN. Multiple databases will be searched in duplicate to identify relevant studies, which will be screened first by title, then by abstract and then by full-text analysis. Results will be collated for comparison. Risk of bias and confidence assessments will be conducted independently by two reviewers, with a third reviewer available if required.
Discussion: Identifying individuals at the highest risk of progression to ESRD is challenging in IgAN, due to the heterogeneity of clinical outcomes. Risk prediction tools have been developed to guide clinicians; however, it is imperative that these aids are accurate and reproducible. The OC is based on observations made by specialist renal pathologists and may be open to observer bias, therefore the utility of prediction models incorporating this classification may be diminished, particularly as in the future novel biomarkers may be incorporated into clinical practice.
Systematic Review Registration: PROSPERO CRD42022364569.
(© 2024. The Author(s).) - References: N Engl J Med. 2009 Jul 2;361(1):11-21. (PMID: 19571279)
Ann Intern Med. 2019 Jan 1;170(1):W1-W33. (PMID: 30596876)
Kidney Int. 2014 Oct;86(4):828-36. (PMID: 24694989)
BMJ. 2015 Mar 16;350:h870. (PMID: 25775931)
JAMA. 2016 Jan 12;315(2):164-74. (PMID: 26757465)
Kidney Int. 2009 Sep;76(5):534-45. (PMID: 19571791)
Pediatr Nephrol. 2017 May;32(5):725-731. (PMID: 27324471)
JAMA. 2017 Aug 1;318(5):432-442. (PMID: 28763548)
Nephrol Dial Transplant. 2020 Jun 1;35(6):1002-1009. (PMID: 30418652)
Lancet. 2018 Nov 10;392(10159):2052-2090. (PMID: 30340847)
Kidney Int. 2012 May;81(9):833-43. (PMID: 22318424)
Kidney360. 2023 Aug 1;4(8):1103-1111. (PMID: 37357346)
Kidney Int. 2020 Oct;98(4):1044-1052. (PMID: 32450154)
Kidney Int. 2009 Sep;76(5):546-56. (PMID: 19571790)
Nephrol Dial Transplant. 2017 Nov 01;32(11):1841-1850. (PMID: 29106593)
Isr Med Assoc J. 2018 Aug;20(8):499-503. (PMID: 30084576)
Ann Intern Med. 2020 Sep 15;173(6):426-435. (PMID: 32658569)
BMJ. 2012 Jan 03;344:d7762. (PMID: 22214758)
Kidney Int Rep. 2019 Jul 23;4(10):1435-1445. (PMID: 31701053)
Clin Kidney J. 2023 Feb 08;16(7):1059-1070. (PMID: 37398689)
J Urol Nephrol (Paris). 1968 Sep;74(9):694-5. (PMID: 4180586)
JAMA Intern Med. 2019 Jul 1;179(7):942-952. (PMID: 30980653)
Clin J Am Soc Nephrol. 2023 Jun 1;18(6):727-738. (PMID: 37055195)
J Clin Med. 2021 Jun 04;10(11):. (PMID: 34200024)
Clin J Am Soc Nephrol. 2019 Oct 7;14(10):1458-1465. (PMID: 31511226)
Kidney Int. 2021 Oct;100(4S):S1-S276. (PMID: 34556256)
Can J Urol. 2016 Feb;23(1):8121-6. (PMID: 26892051)
J Am Soc Nephrol. 2019 May;30(5):866-876. (PMID: 30971457) - Contributed Indexing: Keywords: Chronic kidney disease; Disease progression; End-stage renal disease; Glomerulonephritis; IgA nephropathy; Kidney Failure Risk Equation; Kidney failure; Oxford classification; Prediction tool; Renal biopsy
- Publication Date: Date Created: 20240504 Date Completed: 20240504 Latest Revision: 20240524
- Publication Date: 20240525
- Accession Number: PMC11070080
- Accession Number: 10.1186/s13643-024-02543-y
- Accession Number: 38704598
- Source:
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