Commentary on: Thompson WC. Uncertainty in probabilistic genotyping of low template DNA: A case study comparing STRmix™ and TrueAllele®. J Forensic Sci. 2023;68(3):1049-63.

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  • Author(s): Perlin MW;Perlin MW; Butt N; Butt N; Wilson MR; Wilson MR
  • Source:
    Journal of forensic sciences [J Forensic Sci] 2024 Jul; Vol. 69 (4), pp. 1516-1518. Date of Electronic Publication: 2024 Apr 25.
  • Publication Type:
    Letter
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Blackwell Pub Country of Publication: United States NLM ID: 0375370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-4029 (Electronic) Linking ISSN: 00221198 NLM ISO Abbreviation: J Forensic Sci Subsets: MEDLINE
    • Publication Information:
      Publication: 2006- : Malden, MA : Blackwell Pub.
      Original Publication: [Chicago, Ill.] : Callaghan and Co., 1956-
    • Subject Terms:
      Microsatellite Repeats* ; DNA Fingerprinting* ; DNA* ; Genotype*; Humans ; Uncertainty ; Likelihood Functions ; Polymerase Chain Reaction ; Gene Frequency
    • References:
      Thompson WC. Uncertainty in probabilistic genotyping of low template DNA: a case study comparing STRmix™ and TrueAllele®. J Forensic Sci. 2023;68(3):1049–1063. https://doi.org/10.1111/1556‐4029.15225.
      Perlin MW, Allan WP, Bracamontes JM, Danser KR, Legler MM. Reporting exclusionary results on complex DNA evidence, a case report response to ‘Uncertainty in probabilistic genotyping of low template DNA: A case study comparing STRmix™ and TrueAllele®' software [Preprint]. 2023 [updated May 18, 2023]. Available from: https://ssrn.com/abstract=4449313. Accessed 22 Nov 2023.
      United States v. Damond Reynard Lockett. Judge Brian Jackson. Motion to Suppress Denied: Middle District of Louisiana. 2023.
      Edwards AWF. Likelihood. expanded ed. Baltimore, MD: Johns Hopkins University; 1992.
      Perlin MW, Legler MM, Spencer CE, Smith JL, Allan WP, Belrose JL, et al. Validating TrueAllele® DNA mixture interpretation. J Forensic Sci. 2011;56(6):1430–1447. https://doi.org/10.1111/j.1556‐4029.2011.01859.x.
      Kelly H, Bright J‐A, Coble MD, Buckleton JS. A description of the likelihood ratios in the probabilistic genotyping software STRmix™. WIREs Forensic Sci. 2020;2(6):e1377. https://doi.org/10.1002/wfs2.1377.
      Perlin MW. Explaining the likelihood ratio in DNA mixture interpretation. In: Proceedings of Promega's Twenty First International Symposium on Human Identification; 2010 Oct 12–14; San Antonio, TX. Madison, WI: Promega. 2010.
      National Research Council. Evaluation of forensic DNA evidence: update on evaluating DNA evidence. Washington, DC: National Academies Press; 1996.
      Perlin MW. Efficient construction of match strength distributions for uncertain multi‐locus genotypes. Heliyon. 2018;4(10):e00824. https://doi.org/10.1016/j.heliyon.2018.e00824.
      Perlin MW, inventor. Method, apparatus and computer software program for determining probability of error in identifying evidence. US patent 10,489,233. 2019 Nov 26.
      Perlin MW, inventor. Method, apparatus and computer software program for determining probability of error in identifying evidence. US patent 11,385,955. 2022 Jul 12.
      Perlin MW, Hornyak J, Sugimoto G, Miller K. TrueAllele® genotype identification on DNA mixtures containing up to five unknown contributors. J Forensic Sci. 2015;60(4):857–868. https://doi.org/10.1111/1556‐4029.12788.
      Greenspoon SA, Schiermeier‐Wood L, Jenkins BA. Establishing the limits of TrueAllele® casework: a validation study. J Forensic Sci. 2015;60(5):1263–1276. https://doi.org/10.1111/1556‐4029.12810.
      Bauer DW, Butt N, Hornyak JM, Perlin MW. Validating TrueAllele® interpretation of DNA mixtures containing up to ten unknown contributors. J Forensic Sci. 2020;25(2):380–398. https://doi.org/10.1111/1556‐4029.14204.
      Perlin MW, Sinelnikov A. An information gap in DNA evidence interpretation. PLoS One. 2009;4(12):e8327. https://doi.org/10.1371/journal.pone.0008327.
      Perlin MW, Belrose JL, Duceman BW. New York State TrueAllele® casework validation study. J Forensic Sci. 2013;58(6):1458–1466. https://doi.org/10.1111/1556‐4029.12223.
      Ballantyne J, Hanson EK, Perlin MW. DNA mixture genotyping by probabilistic computer interpretation of binomially‐sampled laser captured cell populations: combining quantitative data for greater identification information. Sci Justice. 2013;53(2):103–114. https://doi.org/10.1016/j.scijus.2012.04.004.
      Perlin MW, Dormer K, Hornyak J, Schiermeier‐Wood L, Greenspoon S. TrueAllele® casework on Virginia DNA mixture evidence: computer and manual interpretation in 72 reported criminal cases. PLoS One. 2014;9(3):e92837. https://doi.org/10.1371/journal.pone.0092837.
      Perlin MW, Dormer K, Hornyak J, Meyers T, Lorenz W. How inclusion interpretation of DNA mixture evidence reduces identification information (A123). In: Proceedings of the 65th Annual Scientific Meeting of the American Academy of Forensic Sciences; 2013 Feb 18–23; Washington, DC. Colorado Springs, CO: American Academy of Forensic Sciences. 2013.
      Perlin MW. Transparency in DNA evidence. Washington, DC: President's Council of Advisors on Science and Technology (PCAST); 2016. Available from: https://www.cybgen.com/information/presentations/2016/PCAST/Perlin‐Transparency‐in‐DNA‐evidence/page.shtml. Accessed 22 Nov 2023.
    • Accession Number:
      9007-49-2 (DNA)
    • Publication Date:
      Date Created: 20240426 Date Completed: 20240626 Latest Revision: 20240626
    • Publication Date:
      20240627
    • Accession Number:
      10.1111/1556-4029.15518
    • Accession Number:
      38664900