Long-Term Impairment From Irritant-Induced Occupational Asthma.

Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9504688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-5948 (Electronic) Linking ISSN: 10762752 NLM ISO Abbreviation: J Occup Environ Med Subsets: MEDLINE

Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: Baltimore, MD : Williams & Wilkins, c1995-

Asthma, Occupational*/chemically induced ; Irritants*/adverse effects ; Quality of Life*; Humans ; Male ; Female ; Middle Aged ; Adult ; Surveys and Questionnaires ; Aged ; Follow-Up Studies ; Employment ; Depression ; Occupational Exposure/adverse effects

Objective: The aim of the study is to assess the long-term physical condition, health-related quality of life, employment, and work ability of irritant-induced asthma (IIA) patients.
Methods: Forty-three IIA patients completed a follow-up questionnaire a median of eight (interquartile range 4-11) years after asthma diagnosis. We compared their results with those of 43 low-molecular-weight (LMW) sensitizer-induced occupational asthma (OA) patients and those of 206 adult-onset asthmatics in the general population.
Results: Of the IIA patients, 40% reported depressive symptoms. Of the <65-year-olds, 56% were employed, of whom 39% assessed their work ability as limited. IIA patients had more difficulty climbing several flights of stairs than LMW-induced OA patients (70% vs 47%, OR = 4.83 95% CI: 1.51-15.47). Most of the IIA patients' outcomes were inferior to those of the adult-onset asthmatics in the general population.
Conclusions: IIA prognosis appeared poor but resembled that of LMW-induced OA.
Competing Interests: Conflicts of interest: None declared.
(Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American College of Occupational and Environmental Medicine.)

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0 (Irritants)

Date Created: 20240418 Date Completed: 20240708 Latest Revision: 20240724

20240726

10.1097/JOM.0000000000003120

38637911