Relationship of the Novel Scoring System for Lower Extremity Venous Thrombosis with Pulmonary Embolism.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Author(s): Kaya AT;Kaya AT; Akman B; Akman B
  • Source:
    Academic radiology [Acad Radiol] 2024 Sep; Vol. 31 (9), pp. 3811-3824. Date of Electronic Publication: 2024 Apr 15.
  • Publication Type:
    Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Association Of University Radiologists Country of Publication: United States NLM ID: 9440159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4046 (Electronic) Linking ISSN: 10766332 NLM ISO Abbreviation: Acad Radiol Subsets: MEDLINE
    • Publication Information:
      Publication: Reston Va : Association Of University Radiologists
      Original Publication: Reston, VA : Association of University Radiologists, c1994-
    • Subject Terms:
      Pulmonary Embolism*/diagnostic imaging ; Pulmonary Embolism*/blood ; Venous Thrombosis*/diagnostic imaging ; Lower Extremity*/diagnostic imaging ; Lower Extremity*/blood supply ; Ultrasonography, Doppler*/methods; Humans ; Female ; Male ; Middle Aged ; Aged ; Retrospective Studies ; Computed Tomography Angiography/methods ; Fibrin Fibrinogen Degradation Products/analysis
    • Abstract:
      Rationale and Objective: To develop a new scoring system, the "Lower extremity venous Doppler ultrasound scoring system" (LEVDUS), to predict the diagnosis of pulmonary embolism (PE) localization in patients with deep vein thrombosis (DVT).
      Methods: This single-center retrospective study included 182 patients aged ≥ 18 years. We used scoring according to thrombosis localization and stage in Doppler US. Patients with PE were divided into three categories based on the pulmonary artery (PA) location on CT pulmonary angiography. LEVDUS values were compared according to the PE classification. The threshold value was determined for the diagnosis of PE in the receiver operating characteristics analysis. Factors affecting the diagnosis of PE were evaluated by logistic regression analysis.
      Results: A total of 182 patients were included (female patients: 55.5% [101/182]). The median age of the patients was 68 (IQR, 56-77). The rates of DVT and PE were 35.2% (64/182) and 52.7% (96/182), respectively. Although the median LEVDUS and d-dimer values in the subsegmental PE group were higher, LEVDUS was statistically significant but d-dimer was not (p = 0.005 and p = 0.022, respectively). In addition, both LEVDUS and d-dimer median values in the other PE groups were statistically significantly higher than the non-PE group (p < 0.001). The cut-off value for the diagnosis of PE was LEVDUS≥ 2.5. LEVDUS was 1.2-fold higher for the presence of PE.
      Conclusion: LEVDUS provides useful information in predicting the presence of PE in patients and provides a common diagnostic language between radiologists and emergency or clinic physicians.
      Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
      (Copyright © 2024 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.)
    • Contributed Indexing:
      Keywords: Classification; Color Doppler Imaging; Computed tomography pulmonary angiography; Deep vein thrombosis; Pulmonary embolism; Reporting & Data Systems
    • Accession Number:
      0 (Fibrin Fibrinogen Degradation Products)
      0 (fibrin fragment D)
    • Publication Date:
      Date Created: 20240416 Date Completed: 20240929 Latest Revision: 20240929
    • Publication Date:
      20240930
    • Accession Number:
      10.1016/j.acra.2024.03.010
    • Accession Number:
      38627131