Comparison of minoxidil sulfotransferase activity between scalp hair, eyebrows, and eyelashes: Implication for minoxidil efficacy for off-label use.

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  • Author(s): Mehta N;Mehta N; Goren A; Goren A
  • Source:
    Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Aug; Vol. 23 (8), pp. 2757-2758. Date of Electronic Publication: 2024 Apr 10.
  • Publication Type:
    Letter; Comparative Study
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Blackwell Science Country of Publication: England NLM ID: 101130964 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-2165 (Electronic) Linking ISSN: 14732130 NLM ISO Abbreviation: J Cosmet Dermatol Subsets: MEDLINE
    • Publication Information:
      Original Publication: Oxford, UK : Blackwell Science, c2002-
    • Subject Terms:
      Minoxidil*/administration & dosage ; Off-Label Use* ; Eyebrows*/drug effects ; Scalp* ; Hair*/drug effects ; Eyelashes*/drug effects ; Sulfotransferases*/metabolism; Humans ; Female ; Adult ; Male
    • References:
      Olsen EA, Whiting D, Bergfeld W, et al. A multicenter, randomized, placebo‐controlled, double‐blind clinical trial of a novel formulation of 5% minoxidil topical foam versus placebo in the treatment of androgenetic alopecia in men. J Am Acad Dermatol. 2007;57(5):767‐774. doi:10.1016/j.jaad.2007.04.012.
      Nguyen B, Hu JK, Tosti A. Eyebrow and eyelash alopecia: a clinical review. Am J Clin Dermatol. 2023;24(1):55‐67. doi:10.1007/s40257-022-00729-5.
      Heymann WR. Coming full circle (almost): low dose oral minoxidil for alopecia. J Am Acad Dermatol. 2021;84(3):613‐614. doi:10.1016/j.jaad.2020.12.053.
      Ramos PM, Gohad P, McCoy J, Wambier C, Goren A. Minoxidil Sulfotransferase Enzyme (SULT1A1) genetic variants predicts response to oral minoxidil treatment for female pattern hair loss. J Eur Acad Dermatol Venereol. 2021;35(1):e24‐e26. doi:10.1111/jdv.16765.
      Roberts J, Desai N, McCoy J, Goren A. Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil in the treatment of female androgenetic alopecia. Dermatol Ther. 2014;27(4):252‐254. doi:10.1111/dth.12130.
      Goren A, Castano JA, McCoy J, Bermudez F, Lotti T. Novel enzymatic assay predicts minoxidil response in the treatment of androgenetic alopecia. Dermatol Ther. 2014;27(3):171‐173. doi:10.1111/dth.12111.
    • Accession Number:
      5965120SH1 (Minoxidil)
      EC 2.8.2.- (Sulfotransferases)
    • Publication Date:
      Date Created: 20240410 Date Completed: 20240725 Latest Revision: 20240725
    • Publication Date:
      20240726
    • Accession Number:
      10.1111/jocd.16322
    • Accession Number:
      38597135