It took a long, long time: Ras and the race to cure cancer.

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  • Additional Information
    • Source:
      Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
    • Publication Information:
      Publication: Cambridge, Ma : Cell Press
      Original Publication: Cambridge, MIT Press.
    • Subject Terms:
      Genes, ras* ; Neoplasms*/genetics ; Neoplasms*/therapy; Humans ; Oncogenes ; Mutation
    • Abstract:
      Discoveries of the roles of RAS oncogenes in cancer development four decades ago opened the door to proving that tumor development is driven by somatic mutations' altering the genomes of cancer cells. These discoveries led to illusions about the simplicity of cancer pathogenesis and how cancer could be cured.
      Competing Interests: Declaration of interests The author declares no competing interests.
      (Copyright © 2024 Elsevier Inc. All rights reserved.)
    • Comments:
      Erratum in: Cell. 2024 Sep 19:S0092-8674(24)01028-6. doi: 10.1016/j.cell.2024.09.010. (PMID: 39303714)
    • Publication Date:
      Date Created: 20240329 Date Completed: 20240401 Latest Revision: 20240920
    • Publication Date:
      20240921
    • Accession Number:
      10.1016/j.cell.2024.02.042
    • Accession Number:
      38552606