Methotrexate toxicity complicating a case of rheumatoid arthritis associated Interstitial Lung Disease: Lessons to learn.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101467888 Publication Model: eCollection Cited Medium: Print ISSN: 1930-0433 (Print) Linking ISSN: 19300433 NLM ISO Abbreviation: Radiol Case Rep Subsets: PubMed not MEDLINE
    • Publication Information:
      Publication: 2015-: Amsterdam : Elsevier
      Original Publication: Seattle, WA : University of Washington, 2006-
    • Abstract:
      Rheumatoid arthritis (RA) is one of the most common types of autoimmune arthritis. It can also involve other organs, including vascular structures, and lungs which are affected in 60% to 80% of cases. Other complications may present as airway infections and drug related pulmonary toxicity. We present the case of 75-year-old male patient of North African decent that was hospitalized initially for chronic dyspnea associated with other systemic manifestations, and in whom we confirmed the diagnosis of Rheumatoid arthritis associated interstitial lung disease. The patient was treated with methotrexate (MTX) and later on, he developed a fatal case of methotrexate related pulmonary toxicity.
      (© 2024 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)
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    • Contributed Indexing:
      Keywords: Interstitial lung disease; Methorexate toxicity; Rheumatoid artheritis
    • Publication Date:
      Date Created: 20240325 Latest Revision: 20240326
    • Publication Date:
      20240326
    • Accession Number:
      PMC10959648
    • Accession Number:
      10.1016/j.radcr.2024.02.036
    • Accession Number:
      38523723