[Pulmonary lipofibroblasts in adults and alveolar regeneration in emphysema].

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  • Additional Information
    • Transliterated Title:
      Lipofibroblastes pulmonaires chez l’adulte et régénération alvéolaire au cours de l’emphysème.
    • Source:
      Publisher: Elsevier-Masson Country of Publication: France NLM ID: 8408032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1776-2588 (Electronic) Linking ISSN: 07618425 NLM ISO Abbreviation: Rev Mal Respir Subsets: MEDLINE
    • Publication Information:
      Publication: <2009- > : Issy-les-Moulineaux Cedex, France : Elsevier-Masson
      Original Publication: Paris ; New York : Masson, c1984-
    • Subject Terms:
      Pulmonary Emphysema* ; Emphysema*/metabolism; Adult ; Humans ; Pulmonary Alveoli ; Lung/physiology ; Regeneration/physiology
    • Abstract:
      Lipofibroblasts form a sub-population of fibroblasts located in the mesenchymal alveolar stem cell niche. They show close proximity with alveolar epithelial type 2 cells and play a key role in alveolar development and lung homeostasis. Their role in various diseases such as acute respiratory distress syndrome, pulmonary fibrosis and emphysema is progressively better understood. Through the activation of signaling pathways such as PPARg lipofibroblasts may help to induce endogenous alveolar regeneration.
      (Copyright © 2024. Published by Elsevier Masson SAS.)
    • Contributed Indexing:
      Keywords: Alveolar regeneration; Cellules souches; Emphysema; Emphysème; Lipofibroblastes; Lipofibroblasts; Régénération alvéolaire; Stem cells
    • Publication Date:
      Date Created: 20240309 Date Completed: 20240415 Latest Revision: 20240415
    • Publication Date:
      20240415
    • Accession Number:
      10.1016/j.rmr.2024.02.015
    • Accession Number:
      38461092