Multivariate Assessment of Inhibitory Control in Youth: Links With Psychopathology and Brain Function.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Sage Country of Publication: United States NLM ID: 9007542 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-9280 (Electronic) Linking ISSN: 09567976 NLM ISO Abbreviation: Psychol Sci Subsets: MEDLINE
    • Publication Information:
      Publication: 2010-> : Thousand Oaks, CA : Sage
      Original Publication: New York, NY : Cambridge University Press, c1990-
    • Subject Terms:
      Psychopathology* ; Attention Deficit Disorder with Hyperactivity*; Humans ; Adolescent ; Child ; Anxiety/psychology ; Brain/diagnostic imaging ; Magnetic Resonance Imaging/methods
    • Abstract:
      Inhibitory control is central to many theories of cognitive and brain development, and impairments in inhibitory control are posited to underlie developmental psychopathology. In this study, we tested the possibility of shared versus unique associations between inhibitory control and three common symptom dimensions in youth psychopathology: attention-deficit/hyperactivity disorder (ADHD), anxiety, and irritability. We quantified inhibitory control using four different experimental tasks to estimate a latent variable in 246 youth (8-18 years old) with varying symptom types and levels. Participants were recruited from the Washington, D.C., metro region. Results of structural equation modeling integrating a bifactor model of psychopathology revealed that inhibitory control predicted a shared or general psychopathology dimension, but not ADHD-specific, anxiety-specific, or irritability-specific dimensions. Inhibitory control also showed a significant, selective association with global efficiency in a frontoparietal control network delineated during resting-state functional magnetic resonance imaging. These results support performance-based inhibitory control linked to resting-state brain function as an important predictor of comorbidity in youth psychopathology.
    • References:
      Neuroimage. 2015 Jan 1;104:69-78. (PMID: 25281800)
      Eur Child Adolesc Psychiatry. 2015 Dec;24(12):1419-22. (PMID: 26564021)
      J Affect Disord. 2021 Oct 1;293:78-89. (PMID: 34174475)
      Clin Psychol Sci. 2017 Jan;5(1):187-189. (PMID: 28286706)
      Trends Cogn Sci. 2006 Mar;10(3):117-23. (PMID: 16460990)
      J Am Acad Child Adolesc Psychiatry. 1997 Apr;36(4):545-53. (PMID: 9100430)
      PLoS One. 2017 Sep 25;12(9):e0184661. (PMID: 28945803)
      Dev Neuropsychol. 2013;38(3):153-66. (PMID: 23573794)
      Brain Behav. 2021 Feb;11(2):e01994. (PMID: 33369286)
      Clin Psychol Sci. 2017;5(5):880-889. (PMID: 29057170)
      Hum Brain Mapp. 2019 Dec 1;40(17):4877-4887. (PMID: 31361385)
      Phys Rev Lett. 2001 Nov 5;87(19):198701. (PMID: 11690461)
      J Am Acad Child Adolesc Psychiatry. 1997 Jul;36(7):980-8. (PMID: 9204677)
      Psychol Bull. 2001 Sep;127(5):571-98. (PMID: 11548968)
      J Psychopathol Clin Sci. 2022 May;131(4):407-421. (PMID: 35511526)
      Trends Cogn Sci. 2013 Dec;17(12):627-40. (PMID: 24183779)
      Nature. 2022 Mar;603(7902):654-660. (PMID: 35296861)
      Dev Cogn Neurosci. 2017 Jun;25:138-144. (PMID: 27527736)
      Mol Psychiatry. 2021 Aug;26(8):4016-4025. (PMID: 31664176)
      Dev Cogn Neurosci. 2019 Apr;36:100607. (PMID: 30579789)
      J Abnorm Psychol. 2017 Jan;126(1):137-148. (PMID: 27748619)
      Trends Cogn Sci. 2011 Oct;15(10):483-506. (PMID: 21908230)
      J Child Psychol Psychiatry. 2012 Nov;53(11):1109-17. (PMID: 22574736)
      BMC Psychiatry. 2022 Mar 5;22(1):166. (PMID: 35247998)
      Annu Rev Psychol. 2013;64:135-68. (PMID: 23020641)
      Child Psychiatry Hum Dev. 2022 Jun;53(3):599-609. (PMID: 33738691)
      Cogn Psychol. 2000 Aug;41(1):49-100. (PMID: 10945922)
      J Am Acad Child Adolesc Psychiatry. 2008 Jul;47(7):808-16. (PMID: 18520957)
      Child Psychiatry Hum Dev. 2023 Apr;54(2):493-507. (PMID: 34655358)
      Dev Psychopathol. 2019 Aug;31(3):917-929. (PMID: 31064595)
      J Int Neuropsychol Soc. 2010 Nov;16(6):1064-76. (PMID: 20719043)
      Trends Cogn Sci. 2017 Apr;21(4):277-289. (PMID: 28274677)
      Acta Psychol (Amst). 2002 Jan;109(1):41-56. (PMID: 11766139)
      J Am Acad Child Adolesc Psychiatry. 2023 Jun;62(6):684-695. (PMID: 36563874)
      Brain Struct Funct. 2017 Dec;222(9):3973-3990. (PMID: 28551777)
      J Abnorm Psychol. 2005 May;114(2):216-22. (PMID: 15869352)
      Cereb Cortex. 2018 Sep 1;28(9):3095-3114. (PMID: 28981612)
      Dev Sci. 2021 Jan;24(1):e13040. (PMID: 33021017)
      Neuroimage. 2010 Sep;52(3):1059-69. (PMID: 19819337)
      Child Psychiatry Hum Dev. 2023 Apr;54(2):366-378. (PMID: 34550506)
      J Am Acad Child Adolesc Psychiatry. 2019 Aug;58(8):768-775.e1. (PMID: 30768398)
      Biol Psychiatry. 2020 Jul 1;88(1):18-27. (PMID: 32199605)
      Curr Dir Psychol Sci. 2012 Feb;21(1):8-14. (PMID: 22773897)
      Neuroimage. 2015 May 15;112:267-277. (PMID: 25770991)
      J Exp Psychol Gen. 2001 Dec;130(4):746-63. (PMID: 11757878)
      J Abnorm Child Psychol. 2007 Oct;35(5):745-58. (PMID: 17668315)
      Annu Rev Neurosci. 2015 Jul 8;38:151-70. (PMID: 26154978)
      Neuropsychopharmacology. 2022 Jan;47(1):90-103. (PMID: 34408276)
      Biol Psychiatry. 2021 Mar 15;89(6):579-587. (PMID: 33386133)
    • Contributed Indexing:
      Keywords: childhood psychopathology; global efficiency; inhibitory control; latent factor; open data; resting-state functional magnetic resonance imaging
    • Publication Date:
      Date Created: 20240306 Date Completed: 20240412 Latest Revision: 20240605
    • Publication Date:
      20240605
    • Accession Number:
      PMC11145514
    • Accession Number:
      10.1177/09567976241231574
    • Accession Number:
      38446868