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Experience of patients on methadone maintenance treatment receiving take-home methadone doses during COVID-19 pandemic: A multi-site study from India.
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- Author(s): Kathiresan P;Kathiresan P; Patel V; Patel V; Jangra J; Jangra J; Chattopadhyay A; Chattopadhyay A; Abdus S; Abdus S; Jadhav M; Jadhav M; Rao R; Rao R; Arya A; Arya A; Bansal PD; Bansal PD; Chinggouman C; Chinggouman C; Bhad R; Bhad R; Ambekar A; Ambekar A; Agrawal A; Agrawal A; Chatterjee B; Chatterjee B; Yadav D; Yadav D
- Source:
Asian journal of psychiatry [Asian J Psychiatr] 2024 May; Vol. 95, pp. 103979. Date of Electronic Publication: 2024 Feb 24.- Publication Type:
Journal Article; Observational Study; Multicenter Study- Language:
English - Source:
- Additional Information
- Source: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101517820 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-2026 (Electronic) Linking ISSN: 18762018 NLM ISO Abbreviation: Asian J Psychiatr Subsets: MEDLINE
- Publication Information: Original Publication: [Amsterdam] : Elsevier
- Subject Terms: Methadone*/administration & dosage ; Methadone*/therapeutic use ; Opiate Substitution Treatment*/methods ; COVID-19* ; Opioid-Related Disorders*/drug therapy; Humans ; India ; Male ; Adult ; Female ; Cross-Sectional Studies ; Middle Aged ; Medication Adherence ; Analgesics, Opioid/administration & dosage
- Abstract: Background: Methadone take-home doses for opioid dependence treatment are strictly regulated due to diversion and overdose concerns, so patients must visit the clinic daily for dispensing. This was also done in India until the COVID-19 pandemic, when lockdown restriction compelled take- home dispensing of methadone. This study examined experience of patients who received take- home methadone during COVID-19 pandemic in India.
Methods: Observational, cross-sectional design. We contacted all consenting methadone centres in India during the lockdown and selected those that provided take-home doses for the study. Patients who received daily methadone before the lockdown and take-home doses after were interviewed using a study-specific questionnaire.
Results: The study had 210 participants. Take-home methadone was dispensed for 2.5 days on average in each dispensing. When taking methadone at home, 3.3% split their dose 25% took less than the prescribed dose to save it for a rainy days, and 3.3% reported an overdose episode. Adherence improved in 58.6% participants after take-home methadone. Participants perceived many benefits from take-home methadone such as reduced hospital visits and travel time to collect methadone, improvement in work, and financial savings. About 54.3% participants reported storing their take-home doses safely, and 1.9% reported that their family consumed methadone by mistake.
Conclusions: Take-home methadone was found to be beneficial to most participants in terms of time saved and improved productivity. Preconceived concerns of providing take-home methadone in terms of its overdose, diversion, or accidental ingestion by others are not commonly seen when individuals are provided take-home doses of methadone.
(Copyright © 2024 Elsevier B.V. All rights reserved.) - Contributed Indexing: Keywords: COVID-19; Methadone; Methadone maintenance treatment; Opioid agonist maintenance treatment; Substance, use Policy; Take-home dispensing
- Accession Number: UC6VBE7V1Z (Methadone)
0 (Analgesics, Opioid) - Publication Date: Date Created: 20240305 Date Completed: 20240511 Latest Revision: 20240610
- Publication Date: 20240611
- Accession Number: 10.1016/j.ajp.2024.103979
- Accession Number: 38442535
- Source:
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