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Association of body mass index and blood pressure variability with 10-year mortality and renal disease progression in type 2 diabetes.
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- Author(s): Fava S;Fava S; Reiff S; Reiff S
- Source:
Acta diabetologica [Acta Diabetol] 2024 Jun; Vol. 61 (6), pp. 747-754. Date of Electronic Publication: 2024 Mar 04.- Publication Type:
Journal Article- Language:
English - Source:
- Additional Information
- Source: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9200299 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-5233 (Electronic) Linking ISSN: 09405429 NLM ISO Abbreviation: Acta Diabetol Subsets: MEDLINE
- Publication Information: Publication: Berlin : Springer Verlag
Original Publication: Berlin : Springer International, c1991- - Subject Terms: Diabetes Mellitus, Type 2*/mortality ; Diabetes Mellitus, Type 2*/physiopathology ; Diabetes Mellitus, Type 2*/complications ; Body Mass Index* ; Blood Pressure* ; Disease Progression*; Humans ; Male ; Female ; Middle Aged ; Aged ; Cardiovascular Diseases/mortality ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/physiopathology ; Diabetic Nephropathies/mortality ; Diabetic Nephropathies/physiopathology ; Glycated Hemoglobin/metabolism ; Glycated Hemoglobin/analysis ; Neoplasms/mortality ; Neoplasms/physiopathology
- Abstract: Background: Variability in biological parameters may be associated with adverse outcomes. The aim of the study was to determine whether variability in body mass index (BMI) and blood pressure is associated with all-cause, cardiovascular mortality and cancer mortality or with renal disease progression in subjects with type 2 diabetes.
Methods: The diabetes database was accessed, and all the information on patient visits (consultations) carried out in the study period (1 January 2008-31 December 2019) was extracted and linked to the laboratory database and the mortality register.
Results: The total number of patients included in the study population was 26,261, of whom 54.4% were male. Median (interquartile range, IQR) age was 60.2 (51.8-68.3) years. The coefficient of variability of BMI was independently associated with increased all-cause and cardiovascular, but not cancer, mortality. Glycated haemoglobin (HbA1c ) was associated with increased all-cause, cardiovascular, and cancer mortality as well as with renal progression. Variability in systolic blood pressure, diastolic blood pressure, and pulse pressure was associated with increased all-cause and cardiovascular mortality in bivariate, but not in multivariate, analyses.
Conclusions: Variability in BMI was associated with increased all-cause and cardiovascular, but not cancer, mortality in a large real-world contemporary population. Our results also confirm the association of HbA1c with increased all-cause, cardiovascular, and cancer mortality as well as with renal progression.
(© 2024. The Author(s).) - References: Clin Nutr. 2011 Dec;30(6):718-23. (PMID: 21764186)
J Cancer Res Clin Oncol. 2023 Sep;149(12):10387-10398. (PMID: 37273108)
J Am Med Dir Assoc. 2023 Mar;24(3):376-381.e1. (PMID: 36592939)
Nutr Rev. 2022 Jun 9;80(7):1755-1768. (PMID: 35182150)
Circulation. 2013 Sep 17;128(12):1325-34. (PMID: 23926207)
Age Ageing. 2023 Jul 1;52(7):. (PMID: 37505989)
Heart. 2023 Sep 28;109(20):1542-1549. (PMID: 37290898)
Curr Obes Rep. 2023 Sep;12(3):264-279. (PMID: 37243875)
Diabetes Care. 2000 Aug;23(8):1097-102. (PMID: 10937504)
Chin Med J (Engl). 2020 Apr 5;133(7):786-791. (PMID: 32195672)
J Surg Oncol. 2016 Feb;113(2):203-8. (PMID: 26799261)
Osteoarthr Cartil Open. 2023 Sep 09;5(4):100407. (PMID: 37744021)
J Steroid Biochem Mol Biol. 2015 Jan;145:103-12. (PMID: 25465477)
Nutrients. 2023 Apr 06;15(7):. (PMID: 37049633)
Lancet. 1998 Sep 12;352(9131):837-53. (PMID: 9742976)
Obesity (Silver Spring). 2017 Jan;25(1):215-222. (PMID: 27768253)
Obes Surg. 2007 Mar;17(3):391-9. (PMID: 17546849)
Int J Obes Relat Metab Disord. 1995 Dec;19(12):862-8. (PMID: 8963353)
Front Med (Lausanne). 2021 May 28;8:672651. (PMID: 34124101)
Cancer Epidemiol Biomarkers Prev. 2017 Jan;26(1):21-29. (PMID: 27986655)
Diabetes Metab J. 2022 Sep;46(5):767-780. (PMID: 35584801)
Obes Rev. 2015 Feb;16 Suppl 1:7-18. (PMID: 25614199)
Eur J Prev Cardiol. 2015 Jul;22(7):940-9. (PMID: 24879358)
Cancer Causes Control. 2010 Apr;21(4):631-42. (PMID: 20094767)
Cochrane Database Syst Rev. 2013 Nov 11;(11):CD008143. (PMID: 24214280)
Circ J. 2005 Jan;69(1):13-8. (PMID: 15635195)
Front Vet Sci. 2021 Dec 13;8:755505. (PMID: 34966805)
J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):2111-2121. (PMID: 34581015)
J Am Heart Assoc. 2023 Jul 4;12(13):e028516. (PMID: 37345834)
Diabetes. 1997 Jan;46(1):3-10. (PMID: 8971073)
Endocrinol Metab Clin North Am. 2008 Sep;37(3):635-46, viii-ix. (PMID: 18775356)
Healthcare (Basel). 2023 Jul 18;11(14):. (PMID: 37510498)
PLoS One. 2020 Nov 9;15(11):e0241930. (PMID: 33166327)
Int J Obes Relat Metab Disord. 2003 Apr;27(4):478-83. (PMID: 12664081)
J Clin Invest. 1997 Sep 1;100(5):1230-9. (PMID: 9276741)
Ann Intern Med. 1993 Oct 1;119(7 Pt 2):749-57. (PMID: 8363210)
J Urol. 2021 Feb;205(2):346-355. (PMID: 32945696)
Int J Obes Relat Metab Disord. 2003 Sep;27(9):1059-65. (PMID: 12917711)
Arch Intern Med. 2009 May 11;169(9):881-6. (PMID: 19433700)
Hepatol Int. 2021 Apr;15(2):482-492. (PMID: 33598868)
Cancer. 2020 Aug 15;126(16):3638-3647. (PMID: 32530506)
Vascul Pharmacol. 2012 Sep-Oct;57(2-4):91-7. (PMID: 22609131)
Diabetes Care. 2017 Feb;40(2):270-279. (PMID: 27899498)
J Am Coll Cardiol. 2016 Sep 27;68(13):1375-1386. (PMID: 27659458)
PLoS One. 2022 Aug 3;17(8):e0272437. (PMID: 35921366)
JAMA Netw Open. 2022 Feb 1;5(2):e220055. (PMID: 35179583)
BMJ. 2000 Aug 12;321(7258):405-12. (PMID: 10938048)
Eur J Clin Nutr. 2015 Aug;69(8):927-32. (PMID: 25369826)
Endocrinol Metab (Seoul). 2020 Dec;35(4):933-942. (PMID: 33397045)
Ageing Res Rev. 2022 Sep;80:101677. (PMID: 35738476)
Diabetes Care. 2020 Sep;43(9):2234-2241. (PMID: 32641375)
Am J Epidemiol. 2012 Apr 15;175(8):785-92. (PMID: 22287640)
Eur J Clin Invest. 2012 Mar;42(3):245-53. (PMID: 21815887)
N Engl J Med. 1991 Jun 27;324(26):1839-44. (PMID: 2041550)
Int J Environ Res Public Health. 2023 Aug 25;20(17):. (PMID: 37681791) - Contributed Indexing: Keywords: BMI variability; Blood pressure variability; Mortality; Renal disease progression; Type 2 diabetes
- Publication Date: Date Created: 20240304 Date Completed: 20240517 Latest Revision: 20240520
- Publication Date: 20240520
- Accession Number: PMC11101579
- Accession Number: 10.1007/s00592-024-02250-z
- Accession Number: 38438789
- Source:
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