Peripartum cardiomyopathy unveiled: Etiology, diagnosis, and therapeutic insights.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7701802 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-6280 (Electronic) Linking ISSN: 01462806 NLM ISO Abbreviation: Curr Probl Cardiol Subsets: MEDLINE
    • Publication Information:
      Publication: [Amsterdam] : Elsevier
      Original Publication: Chicago, Year Book Medical Publishers.
    • Subject Terms:
      Cardiomyopathies*/diagnosis ; Cardiomyopathies*/epidemiology ; Cardiomyopathies*/etiology ; Puerperal Disorders*/diagnosis ; Puerperal Disorders*/epidemiology ; Puerperal Disorders*/etiology ; Heart Failure*/diagnosis ; Heart Failure*/etiology ; Heart Failure*/therapy ; Pregnancy Complications, Cardiovascular*/diagnosis ; Pregnancy Complications, Cardiovascular*/epidemiology ; Pregnancy Complications, Cardiovascular*/etiology; Pregnancy ; Female ; Humans ; Peripartum Period ; Prognosis
    • Abstract:
      Peripartum cardiomyopathy (PPCM) remains a significant challenge in maternal health, marked by its unpredictable onset and varied clinical outcomes. With rising incidence rates globally, understanding PPCM is vital for improving maternal care and prognosis. This review aims to consolidate current knowledge on PPCM, highlighting recent advancements in its diagnosis, management, and therapeutic approaches. This comprehensive review delves into the epidemiology of PPCM, underscoring its global impact and demographic variations. We explore the complex etiology of the condition, examining known risk factors and discussing the potential pathophysiological mechanisms, including oxidative stress and hormonal influences. The clinical presentation of PPCM, often similar yet distinct from other forms of cardiomyopathy, is analyzed to aid in differential diagnosis. Diagnostic challenges are addressed, emphasizing the role of advanced imaging and biomarkers. Current management strategies are reviewed, focusing on the absence of disease-specific treatments and the application of general heart failure protocols. The review also discusses the prognosis of PPCM, factors influencing recovery, and the implications for future pregnancies. Finally, we highlight emerging research directions and the urgent need for disease-specific therapies, aiming to provide a roadmap for future studies and improved patient care. This review serves as a crucial resource for clinicians and researchers, contributing to a deeper understanding and better management of PPCM.
      Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
      (Copyright © 2024 Elsevier Inc. All rights reserved.)
    • Contributed Indexing:
      Keywords: Cardiovascular disease; Clinical cardiology; Peripartum cardiomyopathy; Pregnancy; Women's health
    • Publication Date:
      Date Created: 20240223 Date Completed: 20240402 Latest Revision: 20240402
    • Publication Date:
      20240402
    • Accession Number:
      10.1016/j.cpcardiol.2024.102474
    • Accession Number:
      38395115