In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection.

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  • Additional Information
    • Source:
      Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
    • Publication Information:
      Original Publication: [Amsterdam] : Elsevier B.V., [2014]-
    • Subject Terms:
      COVID-19*; Humans ; SARS-CoV-2 ; Gene Expression Profiling ; Macrophages ; Membrane Proteins
    • Abstract:
      The utilization of single-cell resolved spatial transcriptomics to delineate immune responses during SARS-CoV-2 infection was able to identify M1 macrophages to have elevated expression of IFI27 in areas of infection.
      Competing Interests: Declaration of interests EEK, LP, YK, YL, AN and ML are employees of Nanostring Technologies. KRS is a consultant for Sanofi, Roche and NovoNordisk. The opinions and data presented in this manuscript are of the authors and are independent of these relationships. Other co-authors have no conflict of interest to declare.
      (Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.)
    • Accession Number:
      0 (IFI27 protein, human)
      0 (Membrane Proteins)
    • Publication Date:
      Date Created: 20240220 Date Completed: 20240318 Latest Revision: 20240318
    • Publication Date:
      20240318
    • Accession Number:
      PMC10884333
    • Accession Number:
      10.1016/j.ebiom.2024.105016
    • Accession Number:
      38377798