The Effect of Concomitant Spinal Cord Injury on Postoperative Health-related Quality of Life After Traumatic Subaxial Cervical Spine Injuries: A Nationwide Registry Study.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: W.B. Saunders Country of Publication: United States NLM ID: 2985158R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-821X (Electronic) Linking ISSN: 00039993 NLM ISO Abbreviation: Arch Phys Med Rehabil Subsets: MEDLINE
    • Publication Information:
      Original Publication: Philadelphia, PA : W.B. Saunders
    • Subject Terms:
      Spinal Cord Injuries*/surgery ; Quality of Life* ; Registries* ; Cervical Vertebrae*/surgery ; Cervical Vertebrae*/injuries ; Patient Reported Outcome Measures*; Humans ; Male ; Female ; Middle Aged ; Adult ; Sweden ; Prospective Studies ; Aged ; Disability Evaluation ; Postoperative Period
    • Abstract:
      Objective: To evaluate the effect of spinal cord injury (SCI) on the health-related quality of life (HRQoL) in patients surgically treated for traumatic subaxial cervical spine injuries and investigate the agreement between objective neurologic outcomes and patient reported outcome measures (PROMs) in that context.
      Study Design: Observational study on prospectively collected multi-institutional registry data.
      Setting: Sweden.
      Participants: Patients with traumatic subaxial spine injuries identified in the Swedish Spine Registry (Swespine) between 2006 and 2016.
      Interventions: Anterior, posterior, or anteroposterior cervical fixation surgery.
      Main Outcomes: Patient-reported outcome measures (PROMs) consisting of EQ-5D-3L index and Neck Disability Index (NDI).
      Results: Among the 418 identified patients, 93 (22%) had a concomitant SCI. In this group, 30 (32%) had a complete SCI (Frankel A), and the remainder had incomplete SCIs (17%) Frankel B; 25 (27%) Frankel C; 22 (24%) Frankel D. PROMs significantly correlated with the Frankel grade (P<.001). However, post hoc analysis revealed that the differences between adjacent Frankel grades failed to reach both statistical and clinical significance. On univariable linear regression, the Frankel grade was a significant predictor of a specific index derived from the EQ-5D-3L questionnaire (EQ-5D-3L index ) at 1, 2, and 5 years postoperatively as well as the NDI at 1 and 2 years postoperatively (P<.001). Changes of PROMs over time from 1, to 2, and 5 years postoperatively did not reach statistical significance, regardless of the presence and degree of SCI (P>.05).
      Conclusion: Overall, the Frankel grade significantly correlated with the EQ-5D-3L index and NDI and was a significant predictor of PROMs at 1, 2, and 5 years. PROMs were stable beyond 1 year postoperatively regardless of the severity of the SCI.
      (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
    • Contributed Indexing:
      Keywords: Patient-reported Outcome Measures; Rehabilitation; Surgical approach; Traumatic subaxial cervical spine injury
    • Publication Date:
      Date Created: 20240218 Date Completed: 20240602 Latest Revision: 20240815
    • Publication Date:
      20240815
    • Accession Number:
      10.1016/j.apmr.2024.01.021
    • Accession Number:
      38369229