Tranexamic Acid: An Evergreen Hemostatic Agent.

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  • Additional Information
    • Source:
      Publisher: Thieme Country of Publication: United States NLM ID: 0431155 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-9064 (Electronic) Linking ISSN: 00946176 NLM ISO Abbreviation: Semin Thromb Hemost Subsets: MEDLINE
    • Publication Information:
      Publication: New York, NY : Thieme
      Original Publication: New York, Stratton Intercontinental Medical Book Corp.
    • Subject Terms:
      Tranexamic Acid*/therapeutic use ; Hemostatics*/therapeutic use ; Hemostatics*/pharmacology ; Antifibrinolytic Agents*/therapeutic use; Humans
    • Abstract:
      Tranexamic acid (TXA) is an important antifibrinolytic agent, which inhibits plasminogen activation and fibrinolysis. Several controlled randomized trials have investigated the role of TXA in preventing or decreasing blood loss across different surgical interventions or medical conditions characterized by excessive bleeding, consistently documenting its effectiveness and safety. Although the first clinical use of TXA dates back to more than 60 years ago, TXA remains the focus of intense research. This narrative review summarizes the more recent results and indications on the clinical use of TXA.
      Competing Interests: None declared.
      (Thieme. All rights reserved.)
    • Accession Number:
      6T84R30KC1 (Tranexamic Acid)
      0 (Hemostatics)
      0 (Antifibrinolytic Agents)
    • Publication Date:
      Date Created: 20240209 Date Completed: 20240612 Latest Revision: 20240612
    • Publication Date:
      20240612
    • Accession Number:
      10.1055/s-0044-1779632
    • Accession Number:
      38335995