Effectiveness and continuation rates of the etonogestrel-subdermal contraceptive implant versus short-acting contraceptive methods offered at no cost in Campinas, Brazil.

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  • Additional Information
    • Source:
      Publisher: Wiley Country of Publication: United States NLM ID: 0210174 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3479 (Electronic) Linking ISSN: 00207292 NLM ISO Abbreviation: Int J Gynaecol Obstet Subsets: MEDLINE
    • Publication Information:
      Publication: 2017- : Malden, MA : Wiley
      Original Publication: [New York, NY] Hoeber Medical Division, Harper & Row, [c1969-
    • Subject Terms:
    • Abstract:
      Objectives: To compare the efficacy, reasons for discontinuation and continuation rates of the etonogestrel (ENG)-subdermal contraceptive implant when offered at no cost, and the basis of free choice versus short-acting reversible contraceptive (SARC) methods including combined oral contraceptives (COCs), once-a-month injectables, vaginal ring, and patch.
      Methods: We conducted a prospective study at the University of Campinas, Brazil, involving women aged 18 to 40 years. They were counseled on various contraceptive methods before entering the study and followed up every 3 months for up to 24 months. Satisfaction was assessed using a Likert scale. Survival rates were estimated using the Kaplan-Meier test, and curve comparisons were performed using the log-rank test.
      Results: We enrolled 609 women including 358/609 women (58.8%) who chose the ENG-implant and 251/609 (41.2%) who chose SARC methods. Contraceptive failure and all other reasons for discontinuation were significantly higher in SARC users compared to the ENG-implant users (P < 0.001 and P = 0.002, respectively). The continuation rate was higher among ENG-implant users (89.9% and 75.4%) compared to SARC methods users (27.2% and 15.9%) up to 1 and 2 years after study initiation, respectively. Satisfaction was high in both groups (>82%).
      Conclusions: The ENG-implant showed higher contraceptive effectiveness and higher continuation rates than SARC methods up to 2 years after study initiation. Furthermore, users from both groups were highly satisfied with their contraceptive. The main reason for discontinuing use of the ENG-implant was bothersome uterine bleeding, while for SARC methods it was for personal reasons.
      (© 2024 International Federation of Gynecology and Obstetrics.)
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    • Grant Information:
      573747/2008-3 FAPESP; 2015/20504-9 CNPq
    • Contributed Indexing:
      Keywords: Brazil; continuation rate; contraception; etonogestrel implant; short‐acting contraceptives
    • Accession Number:
      81K9V7M3A3 (Desogestrel)
      304GTH6RNH (etonogestrel)
      0 (Contraceptive Agents, Female)
      0 (Drug Implants)
    • Publication Date:
      Date Created: 20240208 Date Completed: 20240626 Latest Revision: 20240626
    • Publication Date:
      20240626
    • Accession Number:
      10.1002/ijgo.15415
    • Accession Number:
      38328989