Rapid immunoassays for the detection of quinoxalines and their metabolites residues in animal-derived foods: A review.

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  • Additional Information
    • Source:
      Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE
    • Publication Information:
      Publication: Barking : Elsevier Applied Science Publishers
      Original Publication: Barking, Eng., Applied Science Publishers.
    • Subject Terms:
      Quinoxalines*/analysis ; Antibodies*; Animals ; Humans ; Enzyme-Linked Immunosorbent Assay/methods ; Immunoassay ; Haptens/chemistry
    • Abstract:
      Quinoxalines are a class of veterinary drugs with antibacterial and growth-promoting functions. They are often widely used to treat and prevent animal diseases and are illegally used as animal growth promoters to increase economic benefits. Quinoxalines could be easily metabolized in animals to various residue markers and remain in animal-derived foods, which would pose a serious threat to human health. Consequently, it is necessary to detect the residues of quinoxalines and their metabolites. This article reviewed and evaluated immunoassays for quinoxalines and their metabolites in animal-derived foods, mainly including enzyme-linked immunosorbent assays, fluorescence immunosorbent assays, immunochromatography, and surface plasmon resonance biosensors. In addition, we deeply explored the design of haptens for quinoxalines and their metabolites and analyzed the effect of haptens on antibody performance. This paper aims to provide guidance and references for their accurate and sensitive detection, thereby ensuring food safety and human public health.
      Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
      (Copyright © 2024 Elsevier Ltd. All rights reserved.)
    • Contributed Indexing:
      Keywords: Animal-derived foods; Antibody; Hapten design; Immunoassays; Quinoxalines metabolites; Residue detection
    • Accession Number:
      0 (Quinoxalines)
      0 (Antibodies)
      0 (Haptens)
    • Publication Date:
      Date Created: 20240206 Date Completed: 20240227 Latest Revision: 20240227
    • Publication Date:
      20240227
    • Accession Number:
      10.1016/j.foodchem.2024.138539
    • Accession Number:
      38320375