Sonchus oleraceus L.: ethnomedical, phytochemical and pharmacological aspects.

Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

Original Publication: Berlin, New York, Springer Verlag.

Medicine, Traditional* ; Sonchus*/chemistry ; Phytochemicals*/pharmacology ; Phytochemicals*/isolation & purification ; Plant Extracts*/pharmacology ; Plant Extracts*/isolation & purification; Humans ; Animals ; Phytotherapy ; Plants, Medicinal/chemistry ; Ethnopharmacology

Sonchus oleraceus L. (Asteraceae) is a cosmopolitan species native to Europe commonly known as lettuce, sowthistle, chicory, or fake dandelion, considered a weed. However, for many years in various cultures around the world, it has been used as food and medicinal plant. The aim of this integrative review is to document the ethnomedical, phytochemical, and pharmacological information of this species. Forty-one papers document the use of S. oleraceus to heal of a wide variety of diseases. However, gastrointestinal problems, diabetes, inflammation, infections, hepatitis, wounds, and to consume it as food are the most common uses. On the other hand, only 11 items highlight that the main groups of secondary metabolites in this species are flavonoids and terpene lactones. Finally, 45 items reveal that antioxidant, antimicrobial, antiproliferative and cytotoxic were the most studied pharmacological activities. In vitro and in vivo studies of extracts and components isolated from different parts of S. oleraceus have provided a concrete overview of the pharmacological properties of this species that supports its ethnomedical uses in cultures from different parts of the world. The reports of this species have focused solely on the study of the complete plant, leaves, and aerial parts, so it is necessary to study other parts of this species to search for bioactive compounds. No clinical studies were found, which creates an opportunity to expand scientific knowledge of this species.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

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Keywords: Sonchus oleraceus L.; Ethnomedicine; Pharmacology; Phytochemistry

0 (Phytochemicals)
0 (Plant Extracts)

Date Created: 20240202 Date Completed: 20240611 Latest Revision: 20240711

20240712

10.1007/s00210-024-02966-3

38305867