Bacterial polyynes uncovered: a journey through their bioactive properties, biosynthetic mechanisms, and sustainable production strategies.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 8502408 Publication Model: Electronic Cited Medium: Internet ISSN: 1460-4752 (Electronic) Linking ISSN: 02650568 NLM ISO Abbreviation: Nat Prod Rep Subsets: MEDLINE
    • Publication Information:
      Original Publication: [London, England] : Royal Society of Chemistry, c1984-
    • Subject Terms:
      Bacteria*/metabolism ; Polyynes*/chemistry ; Polyynes*/metabolism ; Polyynes*/pharmacology; Molecular Structure ; Biological Products/chemistry ; Biological Products/metabolism ; Biological Products/pharmacology ; Biosynthetic Pathways ; Biotechnology/methods
    • Abstract:
      Covering: up to 2023Conjugated polyynes are natural compounds characterized by alternating single and triple carbon-carbon bonds, endowing them with distinct physicochemical traits and a range of biological activities. While traditionally sourced mainly from plants, recent investigations have revealed many compounds originating from bacterial strains. This review synthesizes current research on bacterial-derived conjugated polyynes, delving into their biosynthetic routes, underscoring the variety in their molecular structures, and examining their potential applications in biotechnology. Additionally, we outline future directions for metabolic and protein engineering to establish more robust and stable platforms for their production.
    • Accession Number:
      25067-58-7 (Polyynes)
      0 (Biological Products)
    • Publication Date:
      Date Created: 20240129 Date Completed: 20240717 Latest Revision: 20240717
    • Publication Date:
      20240717
    • Accession Number:
      10.1039/d3np00059a
    • Accession Number:
      38284321