Associations of dietary inflammatory index with low estimated glomerular filtration rate, albuminuria and chronic kidney disease in U.S adults: Results from the NHANES 2011-2018.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9111474 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1590-3729 (Electronic) Linking ISSN: 09394753 NLM ISO Abbreviation: Nutr Metab Cardiovasc Dis Subsets: MEDLINE
    • Publication Information:
      Publication: 2005- : Amsterdam : Elsevier
      Original Publication: [Heidelberg] : Springer International, c1991-
    • Subject Terms:
      Albuminuria*/diagnosis ; Albuminuria*/epidemiology ; Renal Insufficiency, Chronic*/diagnosis ; Renal Insufficiency, Chronic*/epidemiology ; Renal Insufficiency, Chronic*/complications; Adult ; Humans ; Glomerular Filtration Rate ; Nutrition Surveys ; Diet/adverse effects
    • Abstract:
      Background and Aims: Chronic Kidney Disease (CKD) is characterized by a high inflammation status with ever-increasing prevalence, and defined as low estimated glomerular filtration rate (eGFR) or albuminuria. Both low eGFR and albuminuria can have independent effects on the body. The dietary inflammatory index (DII) is a validated tool used to assess the inflammatory potential of the diet. We aim to explore not only the association between DII and CKD, but also the associations of DII with low eGFR and albuminuria, respectively. In addition, their associations in different subgroups remain to be explored.
      Methods and Results: 18,070 participants from the 2011-2018 NHANES with complete data of dietary intake and laboratory data were involved in our study. The data of 24-hour dietary recall interview was used to calculate DII, CKD could be reflected by laboratory data of creatinine and albumin. Then weighted multivariate logistic regression models and subgroup analyses were performed. The prevalence of low eGFR, albuminuria and CKD were 6.8%, 9.8% and 14.5%, respectively. A positive association between DII and low eGFR was observed (OR=1.12, 95%CI: 1.05-1.21), Q2, Q3 and Q4 are positively associated with a significant 39%, 65% and 71% increased risk of low eGFR compared with Q1 (P for trend<0.05). DII was also associated with CKD (OR=1.06, 95%CI: 1.01-1.11).
      Conclusion: Significant positive associations of DII with CKD and low eGFR were observed. But we didn't find such association between DII and albuminuria.
      Competing Interests: Declaration of competing interest There are no conflicts of interest.
      (Copyright © 2023 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.)
    • Contributed Indexing:
      Keywords: Albuminuria; Chronic kidney disease (CKD); Dietary Inflammatory Index (DII); Estimated Glomerular Filtration Rate (eGFR)
    • Publication Date:
      Date Created: 20240124 Date Completed: 20240318 Latest Revision: 20240318
    • Publication Date:
      20240318
    • Accession Number:
      10.1016/j.numecd.2023.11.006
    • Accession Number:
      38267324