Multiple liquid-liquid extraction of dissolved compounds in immortelle hydrosol with four different solvents.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE
    • Publication Information:
      Original Publication: Zürich, Switzerland : Hoboken, NJ : Verlag Helvetica Chimica Acta ; Distributed in the USA by Wiley, c2004-
    • Subject Terms:
      Hexanes* ; Oils, Volatile*/chemistry; Solvents ; Benzene/analysis ; Chloroform/analysis ; Methylene Chloride/analysis ; Liquid-Liquid Extraction
    • Abstract:
      Immortelle, a revered Mediterranean medicinal plant, is celebrated for its potent essential oil renowned in the cosmetic industry for its skin-enhancing properties. Yet, immortelle hydrosol, an often-overlooked byproduct, holds promise in cosmetics due to its compatibility with polar active ingredients. This study investigates the chemical composition of immortelle hydrosol by employing liquid-liquid extraction (LLE) to transfer volatile organic components into nonpolar solvents. Four solvents - chloroform, dichloromethane, hexane, and benzene - were assessed through ten consecutive extractions from industrially produced immortelle hydrosol. Quantification was achieved using GC analysis with tetradecane as an internal standard. Chloroform emerged as the most efficient solvent, yielding 2447.0 mg/L of volatile compounds, surpassing dichloromethane, hexane, and benzene. Key compounds in immortelle hydrosol included 3-pentanone, 2-methyl-1-butanol, and γ-terpineol. Importantly, the study revealed that a portion of essential oil compounds persists in the hydrosol even after ten LLE cycles, with optimal results achievable in five extractions (~92 % in most cases).
      (© 2023 Wiley-VHCA AG, Zurich, Switzerland.)
    • References:
      H. Chen, P. M. Davidson, Q. Zhong, Appl. Environ. Microbiol. 2014, 80, 907-916.
      P. Tannous, R. Juliani, M. Wang, J. Simon, Water balance in hydrosol production via steam distillation: case study using lavandin (Lavandula x intermedia). New use agriculture and natural plant products. Technical Report. 14 pp. Technical Report submitted to the National Organic Consumer Association 2004.
      S. Price, L. Price, Aromatherapy for Health Professionals, Churchill Livingstone/Elsevier, Philadelphia, PA, 2007, p. 157.
      A. E. Edris, J. Essent. Oil-Bear. Plants 2009, 12, 155-161.
      H. C. Andola, V. K. Purohit, R. S. Chauhan, K. Arunachalam, Med. Plants - Int. J. Phytomed. Relat. Ind. 2014, 6, 161.
      K. Jakubczyk, A. Tuchowska, K. Janda-Milczarek, Biomed. Pharmacother. 2021, 142, 112033.
      A. Sarkic, I. Stappen, Cosmetics 2018, 5, 11.
      Y. Milou, K. Fontes, C. Tourel (L′Occitane FR), US 766454B2, 2010.
      N. Kunc, A. Frlan, D. Baričevič, N. Kočevar Glavač, M. Kokalj Ladan, Plants 2022, 11, 2573.
      J. Paolini, C. Leandri, J.-M. Desjobert, T. Barboni, J. Costa, J. Chromatogr. A 2008, 1193, 37-49.
      C. A. Ferraz, A. C. A. Sousa, D. Caramelo, F. Delgado, A. P. De Oliveira, M. R. Pastorinho, Ind. Crops Prod. 2022, 175, 114232.
      M. Kokalj Ladan, N. Kočevar Glavač, Appl. Sci. 2022, 12, 10040.
      M. H. Shafie, M. L. Kamal, N. A. Abdul Razak, S. Hasan, N. H. Uyup, N. F. Abdul Rashid, Z. Zafarina, Jundishapur J. Nat. Pharm. Prod. 2022, 17, e124018.
      S. Moldoveanu, V. David, Modern Sample Preparation for Chromatography, Elsevier, Amsterdam, 2015, pp. 131-189.
      B. R. Rajeswara Rao, Indian Perfum. 2012, 56, 29-33.
      S. Agarwal, A. Gupta, B. Kapahi, B. Meena, R. Thappa, O. Suri, J. Essent. Oil Res. 2005, 17, 265-267.
      H. S. Canbay, Int. J. Anal. Chem. 2017, 5, 1-7.
      D. A. Wells, Progress in Pharmaceutical and Biomedical Analysis, Elsevier, Amsterdam, 2003, pp. 307-326.
      R. K. Saini, P. Prasad, X. Shang, Y.-S. Keum, Int. J. Mol. Sci. 2021, 22, 13643.
      SGEMC, “Standard Guidelines for the Environmental Monitoring of Chemicals - Analytical Methods”, can be found under https://www.env.go.jp/en/chemi/pops/Appendix/04-GuideLine/04Chapter3.pdf, 2023 (accessed 6 July 2023).
      D. Pljevljakušić, Z. Drinić, Lek. Sirovine 2020, 40, 33-39.
      P. B. Kyle, in Mass Spectrometry for the Clinical Laboratory, Vol. 1 (Eds. H. Nair, W. Clarke), Academic Press, London, 2017, pp. 131-163.
      K. Śmigielski, R. Prusinowska, K. Krosowiak, M. Sikora, J. Essent. Oil Res. 2013, 25, 291-299.
      K. W. Machale, K. Niranjan, V. G. Pangarkar, J. Chem. Technol. Biotechnol. 1997, 69, 362-366.
      F. X. Garneau, G. Collin, H. Gagnon, Am. J. Essent. Oil. Nat. Prod. 2014, 2, 29-35.
      S. H. Yalkowsky, Y. He, Handbook of Aqueous Solubility Data, CRC Press, Boca Raton, Fla, 2003.
      K. Sato, S. Krist, G. Buchbauer, Flavour Fragrance J. 2007, 22, 435-437.
      Z.-L. Wu, Z.-Q. Yin, Y.-H. Du, R.-Z. Feng, K.-C. Ye, Q. Wei, Y. Hu, L. He, L. Liao, Y. Wang, Int. J. Clin. Exp. Pathol. 2014, 7, 6524-6533.
      Z. Wang, K. Yang, L. Chen, R. Yan, S. Qu, Y. Li, M. Liu, H. Zeng, J. Tian, Appl. Microbiol. Biotechnol. 2020, 104, 5039-5052.
      M. L. Coêlho, M. T. Islam, G. Laylson da Silva Oliveira, M. V. Oliveira Barros de Alencar, J. Victor de Oliveira Santos, A. Campinho dos Reis, A. M. Oliveira Ferreira da Mata, M. F. Correia Jardim Paz, A. O. Docea, D. Calina, J. Sharifi-Rad, A. Amélia de Carvalho Melo-Cavalcante, Adv. Pharmacol. Pharm. Sci. 2022, 2022, e8002766.
      W. Mączka, M. Twardawska, M. Grabarczyk, K. Wińska, Antibiotics 2023, 12, 824.
      J. B. Sharmeen, F. M. Mahomoodally, G. Zengin, F. Maggi, Molecules 2021, 26, 666.
      M. De Vincenzi, A. Stammati, A. De Vincenzi, M. Silano, Fitoterapia 2004, 75, 801-804.
      V. Voinchet, A.-M. Giraud-Robert, Phytotherapie 2007, 5, 67-72.
      EPA, “Biopesticide Registration Action Document - 2-Methyl-1-butanol”, can be found under https://www3.epa.gov/pesticides/chem_search/reg_actions/registration/decision_PC-431602_19-Jan-10.pdf (accessed 12 December 2023).
      J. Wei, L. Kang, Plant Signaling Behav. 2011, 6, 369-371.
      M. Giner, J. Avilla, N. De Zutter, M. Ameye, M. Balcells, G. Smagghe, Ind. Crops Prod. 2013, 47, 63-68.
      PubChem (2023a). 3-Pentanone, PubChem Identifier: CID 7288, URL: https://pubchem.ncbi.nlm.nih.gov/compound/3-Pentanone#section=Non-Human-Toxicity-Values (Accessed 12 December 2023).
      PubChem (2023b). Cis-3-Hexen-1-ol, PubChem Identifier: CID 5281167, URL: https://pubchem.ncbi.nlm.nih.gov/compound/cis-3-Hexen-1-ol#section=Non-Human-Toxicity-Values (Accessed 12 December 2023).
      PubChem (2023c). Nerol, PubChem Identifier: CID 643820, URL: https://pubchem.ncbi.nlm.nih.gov/compound/Nerol#section=Non-Human-Toxicity-Values (Accessed 12 December 2023).
      PubChem (2023d). 2-Methyl-1-butanol, PubChem Identifier: CID 8723, URL: https://pubchem.ncbi.nlm.nih.gov/compound/8723#section=Non-Human-Toxicity-Values (Accessed 12 December 2023).
      PubChem (2023e). Carvacrol, PubChem Identifier: CID 10364, URL:https://pubchem.ncbi.nlm.nih.gov/compound/Carvacrol#section=Acute-Effects (Accessed 12 December 2023).
      PubChem (2023f). Allyl heptanoate, PubChem Identifier: CID 8878, URL: https://pubchem.ncbi.nlm.nih.gov/compound/Allyl-heptanoate#section=Acute-Effects (Accessed 12 December 2023).
      D. R. P. Adams, Identification of essential oil components by Gas Chromatography/Mass Spectorscopy, Allured Publishing Corporation, Carol Stream, 2007.
    • Grant Information:
      02/2-062/20-1789 Montenegro Ministry of Science and Technological Development; 451-03-47/2023-01/200003 Ministry of Science, Technological Development and Innovation of the Republic of Serbia
    • Contributed Indexing:
      Keywords: GC-MS; extraction; hydrosol; immortelle; quantification
    • Accession Number:
      0 (Solvents)
      2DDG612ED8 (n-hexane)
      0 (Hexanes)
      J64922108F (Benzene)
      7V31YC746X (Chloroform)
      588X2YUY0A (Methylene Chloride)
      0 (Oils, Volatile)
    • Publication Date:
      Date Created: 20231220 Date Completed: 20240222 Latest Revision: 20240222
    • Publication Date:
      20240222
    • Accession Number:
      10.1002/cbdv.202301528
    • Accession Number:
      38116850