A comparison of the motor effects and analgesic efficacy following lumbar plexus block combined with sciatic nerve block or epidural in dogs undergoing tibial plateau leveling osteotomy.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: United States NLM ID: 100956422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-2995 (Electronic) Linking ISSN: 14672987 NLM ISO Abbreviation: Vet Anaesth Analg Subsets: MEDLINE
    • Publication Information:
      Publication: 2017- : New York, NY : Elsevier
      Original Publication: Oxford, UK : Blackwell Science, c2000-
    • Subject Terms:
      Nerve Block*/veterinary ; Nerve Block*/methods ; Sciatic Nerve*/drug effects ; Osteotomy*/veterinary ; Lumbosacral Plexus*/drug effects; Animals ; Dogs ; Male ; Female ; Pain, Postoperative/veterinary ; Pain, Postoperative/prevention & control ; Tibia/surgery ; Analgesia, Epidural/veterinary ; Analgesia, Epidural/methods ; Prospective Studies ; Bupivacaine/administration & dosage ; Bupivacaine/pharmacology ; Ultrasonography, Interventional/veterinary ; Anesthetics, Local/administration & dosage ; Anesthetics, Local/pharmacology
    • Abstract:
      Objective: To compare motor effects and analgesic efficacy following an ultrasound-guided lateral approach to lumbar plexus blockade at L7 and sciatic nerve blockade (LPSNB) against epidural injection in dogs undergoing tibial plateau leveling osteotomy (TPLO).
      Study Design: Prospective, randomized, blinded clinical trial.
      Animals: A total of 27 healthy adult dogs undergoing unilateral TPLO surgery.
      Methods: Dogs were allocated to either LPSNB (bupivacaine 2 mg kg -1 , 0.75%) or epidural (morphine PF 0.1 mg kg -1 and bupivacaine 0.5 mg kg -1 , 0.75%). Other aspects of clinical management were identical, including anesthetic drug protocol, area of presurgical clipping and bladder care. Time to perform the block, response to surgical stimuli, pain scores, rescue analgesia, time to stand and walk, motor score and time to first urination were recorded. One evaluator, unaware of treatment status, performed all evaluations. Student's t-test or Mann-Whitney U test was used to compare continuous variables between groups, and Fisher's exact test for categorical variables.
      Results: Median (range) times to stand and walk were shorter for LPSNB [60 (40-120) minutes and 90 (60-150) minutes, respectively, p = 0.003] than for epidural [150 (120-240) minutes and 180 (120-360) minutes, respectively, p = 0.006]. Four dogs required rescue intraoperatively (three in epidural group, one in LPSNB group, p = 0.438). Pain scores over the 24 hour evaluation period were similar, and not significantly different, for each group. Time to spontaneous urination [LPSNB, 330 (240-360) minutes; epidural, 300 (120-1440) minutes, p = 1.0] did not differ between groups.
      Conclusions and Clinical Relevance: An ultrasound-guided lateral paravertebral approach to the lumbar plexus within the psoas compartment at L7, combined with sciatic nerve blockade, allows faster return to normal motor function, with similar pain control and impact on urination when compared with epidural in dogs after TPLO surgery.
      (Copyright © 2023 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.)
    • Contributed Indexing:
      Keywords: analgesia; epidural; lumbar plexus; nerve block; ultrasound-guided
    • Accession Number:
      Y8335394RO (Bupivacaine)
      0 (Anesthetics, Local)
    • Publication Date:
      Date Created: 20231215 Date Completed: 20240426 Latest Revision: 20240426
    • Publication Date:
      20250114
    • Accession Number:
      10.1016/j.vaa.2023.10.034
    • Accession Number:
      38102032