Self-reported oral health status, edentulism and all-cause mortality risk in 12 809 Australian older adults: a prospective cohort study.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • Additional Information
    • Source:
      Publisher: Australian Dental Association Country of Publication: Australia NLM ID: 0370612 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1834-7819 (Electronic) Linking ISSN: 00450421 NLM ISO Abbreviation: Aust Dent J Subsets: MEDLINE
    • Publication Information:
      Publication: Sydney : Australian Dental Association
      Original Publication: Sydney.
    • Subject Terms:
    • Abstract:
      Objective: To investigate the association between oral health status and all-cause mortality in older adults using prospective cohort study design.
      Setting and Participants: In total, 12 809 adults aged ≥70 years (54.3% females) were participants of the ASPREE Longitudinal Study of Older Persons (ALSOP).
      Methods: Participants self-reported the presence of natural teeth and oral health status. The association of self-reported oral health, edentulism and the integrative measure of the two with all-cause mortality were explored using the Cox-regression models adjusted for age, gender, socio-economic status, health-related behaviours, weight status, aspirin and polypharmacy. Hazard ratios (HRs) and 95% confidence intervals (CIs) were reported.
      Results: In total, 22.2% of participants reported edentulism and 13.8% had fair/poor oral health. After adjustment for confounders, risk of all-cause mortality was higher among those with edentulism (vs. no edentulism) HR (95% CI) 1.43 (1.18, 1.73); and those with edentulism and reporting poor/fair oral health HR (95% CI) 1.69 (1.02, 2.82), or with no edentulism but reporting poor/fair oral health HR (95% CI) 1.46 (1.19-1.80) vs. no edentulism and reporting good/very good/excellent oral health. No association was observed between self-reported oral health alone and all-cause mortality.
      Conclusions: The risk of all-cause mortality was 69% higher among older adults reporting both edentulism and poor/fair oral health compared with those with teeth and more favourable self-reported oral health. © 2023 Australian Dental Association.
      (© 2023 The Authors. Australian Dental Journal published by John Wiley & Sons Australia, Ltd on behalf of Australian Dental Association.)
    • References:
      Peres MA, Daly B, Guarnizo‐Herreño CC, Benzian H, Watt RG. Oral diseases: a global public health challenge–authors' reply. Lancet 2020;395(10219):186–187.
      Kassebaum NJ, Smith AG, Bernabé E, et al. Global, regional, and national prevalence, incidence, and disability‐adjusted life years for oral conditions for 195 countries, 1990–2015: a systematic analysis for the global burden of diseases, injuries, and risk factors. J Dent Res 2017;96(4):380–387.
      Chen MX, Zhong YJ, Dong QQ, Wong HM, Wen YF. Global, regional, and national burden of severe periodontitis, 1990–2019: an analysis of the Global Burden of Disease Study 2019. J Clin Periodontol 2021;48(9):1165–1188.
      Listl S, Galloway J, Mossey P, Marcenes W. Global economic impact of dental diseases. J Dent Res 2015;94(10):1355–1361.
      Righolt A, Jevdjevic M, Marcenes W, Listl S. Global‐, regional‐, and country‐level economic impacts of dental diseases in 2015. J Dent Res 2018;97(5):501–507.
      UN. World population ageing 2019: highlights United Nations. United Nations, New York: Department of Economic and Social Affairs, Population Division, 2020.
      Loc D. National survey of adult oral health 2017–18, Chapter 4: oral health status. Adelaide, Australia: Australian Research Centre for Population Oral Health, 2019.
      Montini T, Tseng T‐Y, Patel H, Shelley D. Barriers to dental services for older adults. Am J Health Behav 2014;38(5):781–788.
      Tonetti MS, Bottenberg P, Conrads G, et al. Dental caries and periodontal diseases in the ageing population: call to action to protect and enhance oral health and well‐being as an essential component of healthy ageing–consensus report of group 4 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases. J Clin Periodontol 2017;44:S135–S144.
      Takehara S, Wright FC, Naganathan V, et al. A cross‐sectional study of perceived dental treatment needs and oral health status in community‐dwelling older Australian men: the Concord Health and Ageing in Men Project. Int Dent J 2021;71(3):224–232.
      WHO. Oral health. Geneva, Switzerand: World Health Organisation, 2021.
      Aliko A, Wolff A, Dawes C, et al. World Workshop on Oral Medicine VI: clinical implications of medication‐induced salivary gland dysfunction. Oral Surg Oral Med Oral Path Oral Radiol 2015;120(2):185–206.
      Hakeem FF, Bernabé E, Sabbah W. Association between oral health and frailty: a systematic review of longitudinal studies. Gerodontol 2019;36(3):205–215.
      Do L, Ha D, Peres MA, Skinner J, Byun R, Spencer AJ. Effectiveness of water fluoridation in the prevention of dental caries across adult age groups. Community Dent Oral Epidemiol 2017;45(3):225–232.
      Hiratsuka T, Komiyama T, Ohi T, et al. Contribution of systemic inflammation and nutritional status to the relationship between tooth loss and mortality in a community‐dwelling older Japanese population: a mediation analysis of data from the Tsurugaya project. Clinical Oral Investig 2020;24(6):2071–2077.
      Hu H‐Y, Lee Y‐L, Lin S‐Y, et al. Association between tooth loss, body mass index, and all‐cause mortality among elderly patients in Taiwan. Medicine 2015;94(39):e1543.
      Oliveira EJP, Alves LC, Santos JLF, Duarte YA, Bof de Andrade F. Edentulism and all–cause mortality among Brazilian older adults: 11–years follow–up. Brazilian Oral Res 2020;34:34.
      Høvik H, Kolberg M, Gjøra L, et al. The validity of self‐reported number of teeth and edentulousness among Norwegian older adults, the HUNT Study. BMC Oral Health 2022;22(1):82.
      Atala‐Acevedo C, McGrath R, Glenister K, et al. Self‐rated oral health as a valid measure of oral health status in adults living in rural Australia. Healthcare (Basel) 2023;11(12):1721.
      Ramos RQ, Bastos JL, Peres MA. Diagnostic validity of self‐reported oral health outcomes in population surveys: literature review. Rev Bras Epidemiol 2013;16(3):716–728.
      Lundbeck HJ, Smith MB, Thomson WM. Clinical validity of self‐rated oral health among New Zealand nursing home residents. Gerodontol 2020;37(3):253–257.
      Pattussi MP, Peres KG, Boing AF, Peres MA, Da Costa JSD. Self‐rated oral health and associated factors in Brazilian elders. Community Dent Oral Epidemiol 2010;38(4):348–359.
      McNeil JJ, Woods RL, Ward SA, et al. Cohort profile: the ASPREE longitudinal study of older persons (ALSOP). Int J Epidemiol 2019;48(4):1048–1049h.
      Ernst ME, Broder JC, Wolfe R, et al. Health characteristics and aspirin use in participants at the baseline of the ASPirin in reducing events in the elderly – eXTension (ASPREE‐XT) observational study. Contemp Clin Trials 2023;130:107231.
      McNeil JJ, Nelson MR, Woods RL, et al. Effect of aspirin on all‐cause mortality in the healthy elderly. New Eng J Med 2018;379(16):1519–1528.
      Peng J, Song J, Han J, et al. The relationship between tooth loss and mortality from all causes, cardiovascular diseases, and coronary heart disease in the general population: systematic review and dose–response meta‐analysis of prospective cohort studies. Biosci Rep 2019;39(1):BSR20181773.
      ABS. Socio‐Economic Indexes for Areas. 2011. Available at: https://www.abs.gov.au/websitedbs/censushome.nsf/home/seifa. Accessed 5 May 2023.
      ABS. Remoteness structure. Canberra, Australia: Australian Bureau of Statistics, 2021. Available at: https://www.abs.gov.au/statistics/standards/australian‐statistical‐geography‐standard‐asgs‐edition‐3/jul2021‐jun2026/remoteness‐structure. Accessed 5 May 2023.
      Faizuddin M, Tarannum F, Korla N, Swamy S. Association between long‐term aspirin use and periodontal attachment level in humans: a cross‐sectional investigation. Australian Dent J 2012;57(1):45–50.
      Hämäläinen P, Meurman JH, Kauppinen M, Keskinen M. Oral infections as predictors of mortality. Gerodontology 2005;22(3):151–157.
      Österberg T, Carlsson GE, Sundh V, Mellström D. Number of teeth–a predictor of mortality in 70‐year‐old subjects. Community Dent Oral Epidemiol 2008;36(3):258–268.
      Paganini‐Hill A, White SC, Atchison KA. Dental health behaviors, dentition, and mortality in the elderly: the leisure world cohort study. J Aging Res 2011;2011:1–10.
      Kotronia E, Wannamethee SG, Papacosta AO, et al. Poor oral health and inflammatory, hemostatic, and cardiac biomarkers in older age: results from two studies in the UK and USA. J Gerontol: Series A 2021;76(2):346–351.
      Joshy G, Arora M, Korda RJ, Chalmers J, Banks E. Is poor oral health a risk marker for incident cardiovascular disease hospitalisation and all‐cause mortality? Findings from 172 630 participants from the prospective 45 and up study. BMJ Open 2016;6(8):e012386.
      Petersen PE, Kandelman D, Arpin S, Ogawa H. Global oral health of older people‐call for public health action. Community Dent Health 2010;27(4):257–267.
      Sheiham A, Steele J, Marcenes W, et al. The relationship among dental status, nutrient intake, and nutritional status in older people. J Dent Res 2001;80(2):408–413.
      Söderström L, Rosenblad A, Adolfsson ET, Bergkvist L. Malnutrition is associated with increased mortality in older adults regardless of the cause of death. Brit J Nutr 2017;117(4):532–540.
      Maida CA, Marcus M, Spolsky VW, Wang Y, Liu H. Socio‐behavioral predictors of self‐reported oral health‐related quality of life. Qual Life Res 2013;22(3):559–566.
      Borrell LN, Baquero MC. Self‐rated general and oral health in New York city adults: assessing the effect of individual and neighborhood social factors. Community Dent Oral Epidemiol 2011;39(4):361–371.
      Thomson WM, He S, Elani H. Self‐report oral health and disease experience among adults in China and NZ. Clin Oral Investig 2019;23:2123–2128.
      Bassim CW, MacEntee MI, Nazmul S, et al. Self‐reported oral health at baseline of the Canadian longitudinal study on aging. Community Dent Oral Epidemiol 2020;48(1):72–80.
      Hakeem FF, Bernabé E, Sabbah W. Self‐rated oral health and frailty index among older Americans. Gerodontology 2021;38(2):185–190.
      Lawal FB. Global self‐rating of oral health as summary tool for oral health evaluation in low‐resource settings. J Int Soc Prev Community Dent 2015;5(Suppl 1):S1–S6.
      Knäuper B, Carrière K, Chamandy M, Xu Z, Schwarz N, Rosen NO. How aging affects self‐reports. Eur J Ageing 2016;13(2):185–193.
      Watt RG, Daly B, Allison P, et al. The Lancet oral health series: implications for oral and dental research. J Dent Res 2020;99(1):8–10.
    • Grant Information:
      IG1173690 National Health and Medical Research Council; 101927 National Heart Foundation of Australia Postdoctoral Fellowship
    • Contributed Indexing:
      Keywords: Cohort study; edentulism; mortality; oral health; tooth loss
    • Publication Date:
      Date Created: 20231102 Date Completed: 20240523 Latest Revision: 20240523
    • Publication Date:
      20240523
    • Accession Number:
      10.1111/adj.12987
    • Accession Number:
      37916480